Table 2: Histopathological features of the primary tumors
Complete response (n = 3)* | Major response (n = 10) | Minor response (n = 34)* | |
Differentiation | Low grade 1 (50%) High grade 1 (50%) | Low grade 3 (30%) High grade 7 (70%) | Low grade 27 (84.5%) High grade 5 (15.5%) |
Location | Colon 0 Sigmoid-rectum 3 (100%) | Colon 3 (30%) Sigmoid-rectum 7 (70%) | Colon 13 (38%) Sigmoid-rectum 21 (62%) |
Lymph vessel invasion | Present 0 Absent 2 (100%) | Present 1 (10%) Absent 9 (90%) | Present 8 (25%) Absent 24 (75%) |
Lymphohistiocytic Inflammatory reaction | Absent 1 (50%) Scarce 1 (50%) Intense 0 | Absent 5 (50%) Scarce 3 (30%) Intense 2 (20%) | Absent 17 (53%) Scarce 6 (19%) Intense 9 (28%) |
Leading front | Pushing 0 Infiltrative 2 (100%) | Pushing 3 (30%) Infiltrative 7 (70%) | Pushing 9 (28%) Infiltrative 23 (72%) |
Desmoplasia | Absent 2 (100%) Present 0 | Absent 7 (70%) Present 3 (30%) | Absent 28 (87.5%) Present 4 (12.5%) |
Mucin production | Absent 2 (100%) Present 0 | Absent 10 (10%) Present 0 | Absent 27 (84.4%) Present 5 (15.6%) |
pT stage | T1 0 T2 1 (33%) T3 2 (64%) T4 0 | T1 1 (10%) T2 1 (10%) T3 7 (70%) T4 1 (10%) | T1 0 T2 2 (6%) T3 29 (85%) T4 3 (9%) |
pN stage | N0 3 (100%) N1 0 N2 0 | N0 4 (40%) N1 2 (20%) N2 4 (40%) | N0 15 (44%) N1 13 (38%) N2 6 (8%) |
*Histopathological data of the primaries were missing in one patient from the complete response group and two from the minor response group |