Table 2: Histopathological features of the primary tumors

Complete response (n = 3)* Major response (n = 10) Minor response (n = 34)*
Differentiation Low grade 1 (50%) High grade 1 (50%) Low grade 3 (30%) High grade 7 (70%) Low grade 27 (84.5%) High grade 5 (15.5%)
Location Colon 0 Sigmoid-rectum 3 (100%) Colon 3 (30%) Sigmoid-rectum 7 (70%) Colon 13 (38%) Sigmoid-rectum 21 (62%)
Lymph vessel invasion Present 0 Absent 2 (100%) Present 1 (10%) Absent 9 (90%) Present 8 (25%) Absent 24 (75%)
Lymphohistiocytic Inflammatory reaction Absent 1 (50%) Scarce 1 (50%) Intense 0 Absent 5 (50%) Scarce 3 (30%) Intense 2 (20%) Absent 17 (53%) Scarce 6 (19%) Intense 9 (28%)
Leading front Pushing 0 Infiltrative 2 (100%) Pushing 3 (30%) Infiltrative 7 (70%) Pushing 9 (28%) Infiltrative 23 (72%)
Desmoplasia Absent 2 (100%) Present 0 Absent 7 (70%) Present 3 (30%) Absent 28 (87.5%) Present 4 (12.5%)
Mucin production Absent 2 (100%) Present 0 Absent 10 (10%) Present 0 Absent 27 (84.4%) Present 5 (15.6%)
pT stage T1 0 T2 1 (33%) T3 2 (64%) T4 0 T1 1 (10%) T2 1 (10%) T3 7 (70%) T4 1 (10%) T1 0 T2 2 (6%) T3 29 (85%) T4 3 (9%)
pN stage N0 3 (100%) N1 0 N2 0 N0 4 (40%) N1 2 (20%) N2 4 (40%) N0 15 (44%) N1 13 (38%) N2 6 (8%)
*Histopathological data of the primaries were missing in one patient from the complete response group and two from the minor response group