Table 1: Comparison of characteristics by presence of PanIN (n = 1242).
|
Characteristics |
All patients (n = 1242) n (%) |
PanIN |
|
|
|
With (n = 729) n (%) |
Without (n = 513) n (%) |
P value |
||
|
Age (in years), median |
62 [IQR: 52-70] |
64 [IQR: 56-72] |
58 [IQR: 43-68] |
< 0.00001*a |
|
Gender |
|
|
|
|
|
Female |
578 (47) |
349 (48) |
229 (45) |
0.261b |
|
Male |
664 (53) |
380 (52) |
284 (55) |
|
|
Diagnosis |
|
|
|
|
|
Pancreatic ductal carcinoma |
344 (28) |
312 (43) |
32 (6) |
< 0.0001*c |
|
IPMN |
79 (6) |
62 (9) |
17 (3) |
|
|
MCN |
35 (3) |
23 (3) |
12 (2) |
|
|
Neuroendocrine Neoplasm |
73 (6) |
33 (5) |
40 (8) |
|
|
Non-ductal cancer |
39 (3) |
6 (1) |
33 (6) |
|
|
Non-pancreatic cancer |
424 (34) |
185 (25) |
239 (47) |
|
|
Non-tumoral |
248 (20) |
108 (15) |
140 (27) |
|
|
Smoking history [n = 1226] |
|
|
|
|
|
No |
974 (79) |
577 (80) |
397 (79) |
0.625b |
|
Yes |
252 (21) |
145 (20) |
107 (21) |
|
|
Alcohol intake history [n = 1224] |
|
|
|
|
|
No |
999 (82) |
589 (82) |
410 (82) |
0.967b |
|
Yes |
225 (18) |
133 (18) |
92 (18) |
|
|
Diabetes [n = 1226] |
|
|
|
|
|
No |
935 (76) |
515 (71) |
420 (83) |
<0.0001*b |
|
Yes |
291 (24) |
207 (29) |
84 (17) |
|
aMann Whitney U test was used; bChi square test was used; cFisher’s Exact test was used
PanIN: Pancreatic Intraepithelial Neoplasia; IQR: Interquartile Range; IPMN: Intraductal Papillary Mucinous Neoplasm; MCN: Mucinous Cystic Neoplasm