Table 2: Association between patient characteristics and presence of PanIN (n = 1224).

 

Crude OR

P value

Adjusted OR

P value

Age (in years)

1.04 (1.03-1.05)

< 0.0001*

1.03 (1.02-1.04)

< 0.0001*

Gender

 

 

 

 

 Female

Ref

Ref

-

-

 Male

0.87 (0.69-1.10)

0.246

-

-

Diagnosis

 

 

 

 

 Pancreatic ductal cancer

Ref

Ref

Ref

Ref

 IPMN

0.37 (0.20-0.72)

0.003*

0.39 (0.20-0.76)

0.006*

 MCN

0.20 (0.09-0.43)

< 0.0001*

0.37 (0.16-0.86)

0.020*

 Neuroendocrine Neoplasm

0.08 (0.05-0.15)

< 0.0001*

0.12 (0.06-0.22)

< 0.0001*

 Non-ductal cancer

0.02 (0.01-0.05)

< 0.0001*

0.04 (0.02-0.12)

< 0.0001*

 Non-pancreatic cancer

0.08 (0.05-0.12)

< 0.0001*

0.08 (0.05-0.12)

< 0.0001*

 Non-tumoral

0.08 (0.05-0.12)

< 0.0001*

0.11 (0.07-0.18)

< 0.0001*

Smoking history

 

 

 

 

 No

Ref

Ref

-

-

 Yes

0.93 (0.70-1.23)

0.600

-

-

Alcohol intake history

 

 

 

 

 No

Ref

Ref

-

-

 Yes

1.01 (0.75-1.35)

0.967

-

-

Diabetes

 

 

 

 

 No

Ref

Ref

-

-

 Yes

2.00 (1.50-2.66)

<0.0001*

-

-

Ref: Reference category; PanIN: Pancreatic Intraepithelial Neoplasia; OR; Odds Ratio; IPMN: Intraductal Papillary Mucinous Neoplasm; MCN: Mucinous Cystic Neoplasm