Table 2: Association between patient characteristics and presence of PanIN (n = 1224).
|
Crude OR |
P value |
Adjusted OR |
P value |
Age (in years) |
1.04 (1.03-1.05) |
< 0.0001* |
1.03 (1.02-1.04) |
< 0.0001* |
Gender |
|
|
|
|
Female |
Ref |
Ref |
- |
- |
Male |
0.87 (0.69-1.10) |
0.246 |
- |
- |
Diagnosis |
|
|
|
|
Pancreatic ductal cancer |
Ref |
Ref |
Ref |
Ref |
IPMN |
0.37 (0.20-0.72) |
0.003* |
0.39 (0.20-0.76) |
0.006* |
MCN |
0.20 (0.09-0.43) |
< 0.0001* |
0.37 (0.16-0.86) |
0.020* |
Neuroendocrine Neoplasm |
0.08 (0.05-0.15) |
< 0.0001* |
0.12 (0.06-0.22) |
< 0.0001* |
Non-ductal cancer |
0.02 (0.01-0.05) |
< 0.0001* |
0.04 (0.02-0.12) |
< 0.0001* |
Non-pancreatic cancer |
0.08 (0.05-0.12) |
< 0.0001* |
0.08 (0.05-0.12) |
< 0.0001* |
Non-tumoral |
0.08 (0.05-0.12) |
< 0.0001* |
0.11 (0.07-0.18) |
< 0.0001* |
Smoking history |
|
|
|
|
No |
Ref |
Ref |
- |
- |
Yes |
0.93 (0.70-1.23) |
0.600 |
- |
- |
Alcohol intake history |
|
|
|
|
No |
Ref |
Ref |
- |
- |
Yes |
1.01 (0.75-1.35) |
0.967 |
- |
- |
Diabetes |
|
|
|
|
No |
Ref |
Ref |
- |
- |
Yes |
2.00 (1.50-2.66) |
<0.0001* |
- |
- |
Ref: Reference category; PanIN: Pancreatic Intraepithelial Neoplasia; OR; Odds Ratio; IPMN: Intraductal Papillary Mucinous Neoplasm; MCN: Mucinous Cystic Neoplasm