Table 1: Results of serum, fecal, liver and colonic samples analysis from different experimental groups.

 

 

CN

CNDMH

CHOL

CHOLDMH

Initial weight (g)

180 6

166 7

147 7

152 3

Final weight (g)

314 9

297 16

291 16

296 7

Gain weight (g)

134 7

149 7

146 8

144 7

Triglycerides (mg/dl)

82 4

59 4*

85 7

58 5*

Total cholesterol (mg/dl)

128 8

123 8

111 5

105 7

HDL-cholesterol (mg/dl)

36 3

37 2

36 2

34 1

Hepatic cholesterol (mg/dl)

31 2

37 3

35 3

33 2

Fecal Cholesterol (mg/dl)

34 5

24 3

66 3**

69 5++

Bifidobacteria (UFC/g)

4.35 3.391010

8.37 3.101010

9.39 3.641010

4.48 2.811010

Fecal pH

7.0 0.3

7.2 0.3

6.5 0.1

7.1 0.3*

PCNA (%)

5.76 0.91

16.20 1.70

8.44 0.23

20.48 0.37++

ACF/field

0

0.68 0.16

0

0.41 0.50

(AC/ACF)

0

2.52 0.33

0

2.11 0.21

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Results are expressed as mean standard error. * p < 0.01, compared to the group treated with the respective diet without DMH; **compared to CN group; ++compared to CNDMH group. Standard diet (CN); standard diet + cholesterol 1% (CHOL); standard diet + DMH (CNDMH) and standard diet + cholesterol 1%+ DMH (CHOLDMH). PCNA (proliferating cell nuclear antigen), ACF (Aberrant crypt foci) and AC/ACF (aberrant crypt/aberrant crypt foci).