Table 1: Twist1 protein expression in B cells and microenvironment of DLBCL, FL and benign lymph node hyperplasia.
Benign lymph node hyperplasia (7) | DLBCL (28) | FL (24) | |
Twist expression in tumoral cells (FL and DLBCL) or in lymphoid B cells (Benign lymph node hyperplasia) | |||
Negative, n (%) | 7 (100) | 18 (64.3) | 4 (16.7) |
Postitive, n (%) | 0 (0) | 10 (35.7) | 20 (83.3) |
p value | 0.0835 | 0.0001 | |
Twist expression in microenvironnement | |||
0+, n (%) | 3 (42.9) | 11 (39.3) | 4 (16.7) |
1+, n (%) | 2 (28.6) | 6 (21.4) | 12 (50) |
2+, n (%) | 2 (28.6) | 8 (28.6) | 6 (25) |
3+, n (%) | 0 (0) | 3 (10.7) | 2 (8.3) |
Twist expression in microenvironnement | |||
Negative, n (%) | 3 (42.9) | 11 (39.3) | 4 (16.7) |
Positive, n (%) | 4 (57.1) | 17 (60.7) | 20 (83.3) |
p value | 1.00 | 0.3023 |
TWIST positive expression in tumoral cells if > = 5% demonstrated nuclear staining. Immunoreactivity for fusiform stromal cells was semi-quantified as followed: 0-5% negative (0);
5-25% weak positivity (1+); 25-50% moderate positivity (2); > 50% strong positivity (3). Negative cases were 0+ and positive cases were 1+, 2+ and 3+; ne: Not Evaluable.