Table 1: Twist1 protein expression in B cells and microenvironment of DLBCL, FL and benign lymph node hyperplasia.

Benign lymph node hyperplasia (7) DLBCL (28) FL (24)
Twist expression in tumoral cells (FL and DLBCL) or in lymphoid B cells (Benign lymph node hyperplasia)
Negative, n (%) 7 (100) 18 (64.3) 4 (16.7)
Postitive, n (%) 0 (0) 10 (35.7) 20 (83.3)
p value 0.0835 0.0001
Twist expression in microenvironnement
0+, n (%) 3 (42.9) 11 (39.3) 4 (16.7)
1+, n (%) 2 (28.6) 6 (21.4) 12 (50)
2+, n (%) 2 (28.6) 8 (28.6) 6 (25)
3+, n (%) 0 (0) 3 (10.7) 2 (8.3)
Twist expression in microenvironnement
Negative, n (%) 3 (42.9) 11 (39.3) 4 (16.7)
Positive, n (%) 4 (57.1) 17 (60.7) 20 (83.3)
p value 1.00 0.3023

TWIST positive expression in tumoral cells if > = 5% demonstrated nuclear staining. Immunoreactivity for fusiform stromal cells was semi-quantified as followed: 0-5% negative (0);
5-25% weak positivity (1+); 25-50% moderate positivity (2); > 50% strong positivity (3). Negative cases were 0+ and positive cases were 1+, 2+ and 3+; ne: Not Evaluable.