Table 1: Clinicalpathological characteristics and VDR protein expression in patients with urinary bladder carcinoma (n = 74).
|
Characteristics |
Number of patients (%) |
VDR expression |
|
|
Low (n = 26) |
High (n = 48) |
||
|
Age < 60 y ≥ 60 y |
28 (37.8%) 46 (62.2%) |
10 (35.71%) 16 (34.78%) |
18 (64.29%) 30 (65.22%) |
|
Gender Males Females |
53 (71.6%) 21 (28.4%) |
17 (32.08%) 9 (42.86%) |
36 (67.92%) 12 (57.14%) |
|
Histologic type: Urothelial Non-urothelial: -Keratinizing SCC -Non-keratinizing SCC -Adenocarcinoma |
54 (73%) 20 (27%) 9 (12.1%) 7 (9.5%) 4 (5.4%) |
19 (35.19%) 7 (35%) |
35 (64.81%) 13 (65%) |
|
Tumor grade: Low grade High grade |
24 (32.4%) 50 (67.6%) |
8 (33.33%) 18 (36%) |
16 (66.66%) 32 (64%) |
|
Muscle invasion: Absent Present |
34 (45.9%) 40 (54.1%) |
7 (20.59%) 19 (47.50%) |
27 (79.41%) 21 (52.50%) |
|
LN metastasis1 Absent Present |
20 (27.02%) 20 (27.02%) |
7 (35%) 12 (60%) |
13 (65%) 8 (40%) |
|
Necrosis: Absent Present |
43 (58.1%) 31 (41.9%) |
11 (25.58%) 15 (48.39%) |
32 (74.42%) 16 (51.61%) |
|
LV invasion:2 Absent Present |
54 (73%) 20 (27%) |
16 (29.63%) 10 (50%) |
38 (70.37%) 10 (50%) |
|
PN invasion:3 Absent Present |
57 (77%) 17 (23%) |
17 (29.82%) 9 (52.94%) |
40 (70.18%) 8 (47.06%) |
|
Bilharziasis: Absent Present |
48 (64.9%) 26 (35.1%) |
19 (39.58%) 7 (26.92%) |
29 (60.42%) 19 (73.08%) |
1LN, lymph node metastasis were assessed in radical cystectomy specimens only (n = 40)
2LV, lymphovascular
3PN, perineural