Pt # | |
1 | No complications observed |
2 | Exacerbation of skin symptoms after reduction of prednisone dose 7 months after diagnosis. Patient improved after restoring previous prednisone dose and adding HCQ. |
3 | Respiratory tract infection 6 months after diagnosis resulted in one-week break from MTX. |
4 | Severe systemic calcinosis complicated with osteoporosis and concomitant contractures in elbows appeared 2 years and 10 months after diagnosis. Steatohepatitis developed after 8 years of treatment. |
5 | Shock with acute kidney and respiratory failure caused by rhabdomyolysis 4 years after first hospitalization. Hypertriglyceridemia which appeared in the 5th year of treatment. Reappearance of heliotrope rash and muscle weakness after reduction of prednisone dose 8 years and 8 months after beginning of therapy. Prednisone dose was restored 2 months later. Tachycardia and shortness of breath on exertion which appeared in the 9th year of treatment that needed to be treated with metoprolol 25mg/day. |