Studies’ Characteristics

Results found in each study

Authors Year Country

Numbe r of patients

Median age

Sex of participants

ETE

Multif oca- lity

Tumor size

Age

Sex

Race

Histological

type

Vascular Invasion

DSV

1.

Kim J, et al. [31] USA

1075

Median age: 16 years

Males: 204

females: 871

+

p < 0.001

+ p < 0.001

+ p = 0.006

-

-

-

-

-

-

2.

Spinelli

Italy [32]

132

Median age was 14.3 ± 3.5 y

ears (range 4-18 years)

Males: 33 females: 99

+ P < 0.00 (Micr o ETE)

+ P < 0.00

-

-

-

-

-

+

(P = 0.04)

+ (P = 0. 02)

3.

Ngo DQ , et al. Vietnam

[33]

32

≤ 18 y.o. Mean age: 15.5

Males: 6, Females: 26

+ p = 0.041

+ p = 0.028

+ (> 1 cm) p = 0.008

+ (≤ 15 years)  p = 0.028

-

-

-

-

-

4.

Jain NK, et al. [35] USA

45

Mean age: 15.3 y.o.

Males: 8 Females: 37

+ Micro ETE

p = 0.001

-

-

-

-

-

-

-

-

5.

Qureshi SS, et al. India [22]

86

10-14 y.o. Mean age: 12

Males: 37 Females: 49

+ p =

< 0.0001

-

-

-

-

-

-

-

-

6.

Min Y, et al. China [36]

1930

Ages: 10-24 years

Males: 272 Females: 1658

+ p < 0.001

+ p < 0.001

+ (> 5 mm) p < 0.001

-

+

(male) p = 0.005

+

(Asian/Pacific Islander, American Indian/Alaskan Native

p = 0.015

+

(Papillary)

p < 0.001

-

-

7.

Ngo DQ, et al. Vietnam [34]

48

< 18 y.o. Mean age: not mentioned

Males: 16 females: 32

+ p = 0.001

+ p < 0.001

+ ( > 10 mm) p = 0.002

+ (< 15 years) p = 0.021

+ (male) p = 0.011

-

-

-

-

8.

Liang W, et al. China [37]

102

≤ 21y.o. Mean age:17

Males: 26 Females: 76

-

+ p = 0.007

+ p = 0.034

-

-

-

-

-

-

9.

Paik C, et al. [38] USA

75

Mean age 15.0 (6.9-18.9)

Males: 14 Females: 61

-

-

+ p = 0.04

-

-

-

-

-

-

 10.

Total number of patients

 525

Total males: 616

Total females: 2.909