Table 2: Sedative doses before and after the introduction of clonidine.

Sedative agent Pre-clonidine dose Median (IQR) Post-clonidine dose Median (IQR) p

Fentanyl

(mcg/Kg/hour)

2

(1.96-2.22)

1.84

(1-2.01)

0.001

Morphic chloride

(mcg/Kg/hour)

40

(28.4-45)

30

(29.2-31)

0.18

Remifentanil

(mcg/Kg/minute)

0.12

(0.1-0.15)

0.12

(0.1-0.14)

1

Midazolam

(mg/Kg/hour)

0.18

(0.1-0.2)

0.1

(0.0-0.16)

0.001

Propofol

(mg/Kg/hour)

1.5

(1-2.07)

1.1

(0.0-1.7)

0.007

Levomepromazine

(mg/Kg/day)

3.15

(2.22-3.65)

2

(0.42-3.37)

0.028

Chlorpromazine

(mg/Kg/day)

1.86

(1.7-2.3)

1.7

(1.0-2.79)

0.674

Chloral hydrate

(mg/Kg/day)

35

(23.25-40)

34.5

(0.0-41)

0.401

IQR: Interquartile Range.