Table 1: Familial subtypes of hemiplegic migraine with associated gene involved. This case report documents a novel genetic mutation in the ATP1A2 gene in a child with hemiplegic migraine.
| Subtype | Gene | Protein involved | Neuronal ion channel affected |
| Familial hemiplegic migraine type 1 (FHM1) | CACNA1A | Alpha-1 subunit | Voltage-gated Calcium channel |
| Familial hemiplegic migraine type 2 (FHM2) | ATP1A2 | Alpha-2 subunit | Sodium-Potassium ATPase pump |
| Familial hemiplegic migraine type 3 (FHM3) | SCN1A | Alpha-1 subunit | Voltage-gated Sodium channel |