Table 2: The age-related differences in effects of D-PA.
Neonates | Adults | |
Hexobarbital sleeping-time | shortened | no effect |
Heme oxygenase-1 | inhibited | no effect |
Cytochrom- P-450 | increased | no effect |
Catalase | increased | no effect |
Peroxidases | increased | no effect |
LD50 | > 4000 mg/kg (IP) | 500 mg/kg (IV) |
Radioprotection | significant | ? |