Table 2: Baseline neonatal characteristics by dose-delivery interval (n = 659).
Neonatal characteristics |
DDI category 1 < 155 mins (n = 166) |
DDI category 2 155-314 mins (n = 164) |
DDI category 3 314-526.5 mins (n = 165) |
DDI category 4 > 526.5 mins (n = 164) |
P-value |
Gender |
|
|
|
|
0.814 |
Male |
82 (49.4%) |
79 (48.8%) |
77 (47.0%) |
73 (44.5%) |
|
Female |
84 (50.6%) |
83 (51.2%) |
87 (53.0%) |
91 (55.5%) |
|
Gestational age (weeks), median (IQR) |
38.86 (38-40) |
39.29 (38.14-40.21) |
39.29 (38.43-40.14) |
39.71 (38.71-40.29) |
0.001 |
Birthweight (grams), mean +/- SD |
3289.22 +/- 500.71 |
3307.08 +/- 510.77 |
3358.20 +/- 475.59 |
3434.51 +/- 468.78 |
0.034 |
Apgar 1-minute, median (IQR) |
9 (9-9) |
9 (8-9) |
9 (8-9) |
9 (9-9) |
0.023 |
Apgar 1-minute, binary |
|
|
|
|
0.082 |
Less than 7 |
12 (7.2%) |
25 (15.2%) |
16 (9.7%) |
14 (8.5%) |
|
More than 7 |
154 (92.8%) |
139 (84.8%) |
149 (90.3%) |
150 (91.5%) |
|
Apgar 5 minute, median (IQR) |
9 (9-9) |
9 (9-9) |
9 (9-9) |
9 (9-9) |
0.591 |
Apgar 5-minute, binary |
|
|
|
|
0.04 |
Less than 7 |
1 (0.6%) |
7 (4.3%) |
1 (0.6%) |
2 (1.2%) |
|
More than 7 |
165 (99.4%) |
157 (95.7%) |
164 (99.4%) |
162 (98.8%) |
|
Neonatal resuscitation |
|
|
|
|
0.014 |
No |
60 (36.1%) |
36 (22.2%) |
56 (33.9%) |
61 (37.2%) |
|
Yes |
106 (63.9%) |
126 (76.8%) |
108 (65.5%) |
103 (62.8%) |
|
Tactile stimulation |
|
|
|
|
0.018 |
(resuscitation) |
|
|
|
|
|
No |
61 (36.7%) |
39 (24.1%) |
58 (35.4%) |
65 (39.6%) |
|
Yes |
105 (63.3%) |
123 (75.9%) |
106 (64.6%) |
99 (60.4%) |
|
Continuous positive airway |
|
|
|
|
0.047 |
pressure (CPAP) (resuscitation) |
|
|
|
|
|
No |
152 (91.6%) |
134 (82.7%) |
148 (90.2%) |
148 (90.2%) |
|
Yes |
14 (8.4%) |
28 (17.3%) |
16 (9.8%) |
16 (9.8%) |
|
Intermittent positive pressure ventilation (IPPV) (resuscitation) |
|
|
|
|
0.001 |
No |
155 (93.4%) |
135 (83.3%) |
152 (92.7%) |
156 (95.1%) |
|
Yes |
11 (6.6%) |
27 (16.7%) |
12 (7.3%) |
8 (4.9%) |
|
Oxygen therapy (resuscitation) |
|
|
|
|
0.151 |
No |
166 (100.0%) |
160 (98.8%) |
163 (99.4%) |
164 (100.0%) |
|
Yes |
0 (0.0%) |
2 (1.2%) |
1 (0.6%) |
0 (0.0) |
|
Dextrose (resuscitation) |
|
|
|
|
0.253 |
No |
166 (100.0%) |
161 (99.4%) |
164 (100.0%) |
164 (100.0%) |
|
Yes |
0 (0.0%) |
1 (0.6%) |
0 (0.0) |
0 (0.0) |
|
Volume expander (resuscitation) |
|
|
|
|
0.483 |
No |
166 (100.0%) |
161 (99.4%) |
163 (99.4%) |
164 (100.0%) |
|
Yes |
0 (0.0%) |
1 (0.6%) |
1 (0.6%) |
0 (0.0) |
|
External cardiac massage and ventilation (resuscitation) |
|
|
|
|
0.496 |
No |
166 (100.0%) |
161 (99.4%) |
163 (99.4%) |
164 (100.0%) |
|
Yes |
0 (0.0%) |
1 (0.6%) |
1 (0.6%) |
0 (0.0) |
|
Neonatal characteristics |
DDI category 1 < 155 mins (n = 166) |
DDI category 2 155-314 mins (n = 164) |
DDI category 3 314-526.5 mins (n = 165) |
DDI category 4 > 526.5 mins (n = 164) |
P-value |
Transfer to tertiary care centre |
|
|
|
|
0.781 |
No |
165 (99.4%) |
162 (98.8%) |
162 (98.2%) |
162 (98.8%) |
|
Yes |
1 (0.6%) |
2 (1.2%) |
3 (1.8%) |
2 (1.2%) |
|
Admission to special care nursery |
|
|
|
|
0.972 |
No |
130 (78.3%) |
129 (78.7%) |
130 (78.8%) |
125 (76.2%) |
|
Yes |
36 (21.7%) |
35 (21.3%) |
35 (21.2%) |
39 (23.8%) |
|
Respiratory issues (SCN admission) |
|
|
|
|
0.508 |
No |
32 (88.9%) |
30 (14.3%) |
30 (85.7%) |
30 (76.9%) |
|
Yes |
4 (11.1%) |
5 (14.3%) |
5 (14.3%) |
9 (23.1%) |
|
Feeding difficulties |
|
|
|
|
0.786 |
No |
100 (90.1%) |
104 (91.2%) |
106 (87.6%) |
103 (88.0%) |
|
Yes |
11 (9.9%) |
10 (8.8%) |
15 (12.4%) |
14 (12.0%) |
|