Table 1: Patient characteristics and methods used in included studies.
Author (Year) |
Country |
Method |
Subjects |
Intervention |
Outcome |
Sample Size |
Barandouzi [26] |
Iran |
Double blinded RCT |
Neonates |
10 minutes recorded Brahms Lullaby prior venipuncture with or without sucrose vs. control |
Change in PIPP score |
120 |
Bergomi [22] |
Italy |
RCT |
Premature infants |
Recorded Mozart music for 18 minutes maximum vs. glucose vs. control prior to heel lancet |
Change in PIPP score |
35 |
Qiu [11] |
China |
RCT |
Preterm neonates |
Recorded Smart Baby Lullaby from 5 minutes before until 30 minutes after varied painful procedures in combination with touch intervention vs. control |
Change in serum cortisol and PIPP score |
62 |
Shukla [25] |
India |
RCT |
Neonates age 26-36 months AOG |
Recorded Indian classical flute music with or without kangaroo care 10 minutes before until 5 minutes post heel prick procedure vs. control |
Change in PIPP score |
200 |
Tang [24] |
China |
Random, data-analysts-blinded, controlled trial, two parallel arms |
Hospitalized infant |
Chinese lullabies 10 minutes before until 10 minutes after PICC vs. control |
Change in serum cortisol and PIPP score |
60 |
Tekgündüz [23] |
Turkey |
Double-blind, randomized controlled design |
Preterm infants |
Lullabies played during the tracheal tube removal and reinsertion vs. glucose vs. control, time not specified |
Change in PIPP score |
106 |
AOG: Age of Gestation; PICC: Peripherally Inserted Central Catheter; PIPP: Pediatric Infant Pain Profile Scores; RCT: Randomized Controlled Trial