Table 4: Demographic characteristics, clinical manifestations, laboratory findings and underlying disorders between the haemophagocytic syndrome survivor and non-survivor group.
|
Total |
Non-survivor |
Survivor |
|
|||
n |
30 |
13 |
17 |
p < 0.05 |
|||
Age (x ± s) |
55.5 |
± 18.3 |
68 |
58.2-74.5 |
40 |
34-57 |
0.043 |
Women (%) |
16 |
53.30% |
7 |
61.50% |
9 |
47.10% |
1.00 |
Comorbidities (≥ 2) |
5 |
16.70% |
2 |
15.40% |
3 |
17.60% |
1.00 |
Global hospital stay∞ |
35.5 |
20-6008 |
29 |
15.5-39 |
13 |
17-Aug |
0.563 |
Hospital stay previous to the diagnosis and treatment initiation∞ |
16.5 |
8.5-29.8 |
23.5 |
11.5-38.3 |
10 |
17-May |
0.205 |
HScore∞ |
270.5 |
248.2-302.5 |
268 |
251-289 |
274 |
240-304 |
1.00 |
Splenomegaly |
16 |
53.30% |
7 |
53.80% |
9 |
52.90% |
1.00 |
Hepatomegaly |
10 |
33.30% |
5 |
38.50% |
5 |
29.40% |
0.705 |
Hb (g/dL) |
7.1 |
6.4-7.9 |
7.1 |
6.2-7.8 |
7.1 |
6.6-7.8 |
0.094 |
Pt (x109/L) |
13500 |
5000-52500 |
16000 |
11000-44000 |
12 000 |
5000-99000 |
0.281 |
Pt ≤ 100 000 |
25 |
83.30% |
13 |
100% |
12 |
70.60% |
0.052 |
Leu (x109/L) |
1250 |
238-353 |
1300 |
150-3940 |
1400 |
200-3340 |
0.457 |
Neu (x109/L) |
615 |
0-1550 |
1290 |
20-3 300 |
650 |
0-1400 |
0.805 |
Fb (mg/dL) (n = 24) |
171 |
111-358 |
167 |
106-253 |
169 |
103-451 |
0.796 |
Fer (ng/mL) (n = 28) |
15330 |
5 434-38284 |
29063 |
5728-74604 |
13225 |
8287-28729 |
0.108 |
Tg (mmol/L) |
341 |
226-438 |
254 |
184-382 |
471 |
341-604 |
0.053 |
Tg ≥ 160 mg/dl |
25 |
83.30% |
10 |
76.90% |
15 |
88.20% |
0.63 |
AST (U/L) |
139 |
78-406 |
133 |
101-513 |
179 |
101-512.5 |
0.483 |
ALT (U/L) |
162 |
46-389 |
109 |
41-333 |
199 |
99-298 |
0.198 |
LDH (U/L) |
737 |
521-1 126 |
956 |
602-1 282 |
845 |
564-1 932 |
0.363 |
T.B. (mg/dL) |
2.1 |
1-11.2 |
3.4 |
1.4-17.8 |
2.5 |
1.1-12.4 |
0.145 |
INR (n = 29) |
1.5 |
1.1-1.9 |
2.1 |
1.2-3.7 |
1.5 |
1.1-1.6 |
0.028 |
T.P. (n = 29) |
4.8 |
± 1.04 |
4.7 |
3.9-4.9 |
4.6 |
4.3-5.6 |
0.199 |
A.P. |
234 |
121-413 |
204 |
144-481 |
388 |
104-491 |
0.869 |
GGT |
233 |
110-548 |
239 |
120-427 |
491 |
119-681 |
0.902 |
A.P.: Alkaline Phosphatase; GGT: Gamma glutamyl Transferase.