Baseline

Last observation

Change

P value

Haematology

Haemoglobin (g/dL)

N

58

39

Median

11.45

11.6

0.15

0.832

IQR

9.15-12.80

9.90-12.70

Haematocrit (%)

N

52

33

Median

35.2

34.2

-1

0.226

IQR

30.15-40.23

31.80-37.45

Red blood cells (x 10¹²/L)

N

51

33

Median

4

3.89

-0.11

0.079

IQR

3.20-4.43

3.13-4.41

Leucocytes (x 10⁹/L)

N

58

39

Median

9.07

5.55

-3.52

0.001

IQR

5.89-19.05

4.50-7.80

Neutrophils (x 10⁹/L)

N

53

30

Median

4.27

3.16

-1.11

0.043

IQR

2.77-7.59

2.12-4.56

Lymphocytes (x10⁹/L)

N

52

27

Median

2

1.99

-0.01

0.105

IQR

1.42-4.88

1.30-2.66

Monocytes (x10⁹/L)

N

41

19

Median

0.45

0.55

0.1

0.504

IQR

0.20-0.80

0.26-0.86

Basophils (x10⁹/L)

N

39

16

Median

0.01

0

-0.01

0.055

IQR

0.00-0.07

0.00-0.08

Eosinophils (x10⁹/L)

N

39

16

Median

0.06

0.04

-0.02

0.716

IQR

0.00-0.30

0.00-0.30

Platelets (x10⁹/L)

N

58

39

Median

236.5

200

-36.5

0.017

IQR

152.25-353.25

127.00-267.00

Laboratory data

ALT (U/L)

N

51

26

Median

19

26.5

7.5

0.278

IQR

13.00-31.00

13.65-43.35

AST (U/L)

N

50

26

Median

23

26.5

3.5

0.018

IQR

18.00-35.98

19.75-37.40

ALP (U/L)

N

48

26

Median

162

143

-19

0.456

IQR

80.75-263.50

99.75-170.00

Total bilirubin (mg/L)

N

41

20

Median

4.62

5.65

1.03

0.001

IQR

3.21-8.05

4.58-10.75

Serum creatinine (mg/L)

N

54

31

Median

8.89

8.17

-0.72

0.287

IQR

7.05-10.02

7.00-11.00