Consecutive patients who underwent traditional SPECT myocardial perfusion imaging (MPI) are compared to consecutive patients who underwent SPECT/CT MPI. The subgroup from each cohort that underwent clinically-indicated invasive coronary angiography (ICA) within one year is also compared. For continuous variables, the standard deviation is included in parentheses.

Table 1: Consecutive patients who underwent traditional SPECT myocardial perfusion imaging (MPI) are compared to consecutive patients who underwent SPECT/CT MPI. The subgroup from each cohort that underwent clinically-indicated invasive coronary angiography (ICA) within one year is also compared. For continuous variables, the standard deviation is included in parentheses.

	All patients undergoing MPI			Those with ICA within one year
	SPECT (n = 277)	SPECT-CT (n = 273)		SPECT (n = 36)	SPECT-CT (n = 26)
MPI read as abnormal	31%	35%	p = 0.36	81%^*	88%^*	p = 0.50
Hyperlipidemia	65%	63%	p = 0.59	69%	88%^*	p = 0.12
Diabetes	47%	44%	p = 0.49	64%	54%	p = 0.45
Hypertension	85%	82%	p = 0.49	86%	92%	p = 0.69
Mean BMI	30.8 (7)	29.9 (5)	p = 0.12	30.5 (5.8)	30.4 (4.7)	p = 0.93
Mean age	65.1 (11)	64.5 (11)	p = 0.48	63.8 (9.0)	69.7 (10.4)	p = 0.02
Percent male	50%	56%	p = 0.20	75%^*	65%	p = 0.57
Known CAD	28%	33%	p = 0.20	58%^*	46%	p = 0.44
Prior revascularization	21%	18%	p = 0.45	47%^*	35%^*	p = 0.44
PCI	11%	13%	p = 0.59	31%^*	23%	p = 0.58
CABG	11%	6%	p = 0.05	22%	12%	p = 0.33
Mean LVEF	58 (16)	60 (14)	p = 0.94	47 (16)^*	51 (17)^*	p = 0.41
Exercise tests	30%	26%	p = 0.30	33%	23%	p = 0.41
Pharmacologic tests	70%	74%	p = 0.30	67%	77%	p = 0.41

BMI: body mass index; CAD: coronary artery disease; PCI: percutaneous intervention; CABG: coronary artery bypass graft; LVEF: left ventricular ejection fraction.; ^*Variable is significantly different between those who underwent ICA and those who did not.