Table 2: The prevalence of true positive (TP), false positive (FP), true negative (TN), and false negative (FN) myocardial perfusion imaging (MPI) studies is compared for patients within each cohort that underwent clinically-indicated invasive coronary angiography (ICA) within one year. Positive predictive value (PPV) and sensitivity are calculated for each of the three coronary artery distributions and for the study as a whole.
|
Prevalence of different test outcomes (among patients who also had ICA) |
SPECT
(n = 36)
|
SPECT-CT
(n = 26)
|
|
|
SPECT
(n = 36)
|
SPECT-CT
(n = 26)
|
|
TP |
FP |
LAD |
22% |
42% |
p = 0.10 |
LAD |
25% |
4% |
p = 0.04 |
LCx |
19% |
23% |
p = 0.76 |
LCx |
19% |
8% |
p = 0.28 |
RCA |
33% |
42% |
p = 0.79 |
RCA |
22% |
8% |
p = 0.17 |
Overall |
25% |
62% |
p = 0.008 |
Overall |
56% |
19% |
p = 0.00 |
FN |
TN |
LAD |
14% |
27% |
p = 0.33 |
LAD |
39% |
27% |
p = 0.42 |
LCx |
8% |
35% |
p = 0.02 |
LCx |
53% |
35% |
p = 0.20 |
RCA |
3% |
25% |
p = 0.02 |
RCA |
42% |
25% |
p = 0.18 |
Overall |
6% |
12% |
p = 0.64 |
Overall |
14% |
8% |
p = 0.69 |
PPV |
SPECT |
SPECT-CT |
LAD |
0.47 |
(0.23 to 0.71) |
0.92 |
(0.76 to 1) |
LCx |
0.5 |
(0.24 to 0.76) |
0.75 |
(0.45 to 1) |
RCA |
0.6 |
(0.39 to 0.81) |
0.83 |
(0.62 to 1) |
Overall |
0.28 |
(0.11 to 0.44) |
0.76 |
(0.58 to 0.94) |
Sensitivity |
LAD |
0.62 |
(0.35 to 0.90) |
0.61 |
(0.38 to 0.80) |
LCx |
0.7 |
(0.42 to 0.98) |
0.4 |
(0.15 to 0.64) |
RCA |
0.92 |
(0.78 to 1) |
0.63 |
(0.39 to 0.86) |
Overall |
0.8 |
(0.62 to 0.98) |
0.84 |
(0.68 to 0.94) |