Table 2: Comparison between the survivors and non-survivors regarding different clinical, physiological, radiological and laboratory variables.

Variable

Survivors (n = 25)

Non-survivors (n = 8)

p value

Age (years)

55.2 6.9

61.1 9.4

0.091

Smoking History

Current smoker

Smoking index

 

8 (32%)

38.7 25.4

 

2 (25%)

46.3 11.9

 

FEp = 1.0

0.13

BMI (kg/m2)

29.8 7.8

21.6 4.2

0.008*

Dyspnea (MMRC scale)

2.4 0.9

3.6 0.5

0.001*

Comorbidities

18 (72%)

6 (75%)

FEp = 1.0

mPAP

31 6.1

32.1 12

0.643

Exacerbation ≥ 3 times/yr; Y/N

16/9 (64%)

6/2 (75%)

FEp = 0.687

Failure of NIV trial; Y/N (%)

4/21 (16%)

4/4 (50%)

FEp = 0.074

Plain chest X-ray [n (%)]

Consolidative patcha,

Consolidative patch 14th day

 

11 (44%)

1 (4%)

 

4 (50% )

2 (25%)$

 

FEp = 1.0

FEp = 0.01*

Laboratory investigations

heamatocrit (%)

 

49.8 7.5

 

43.8 7.6

 

0.101

Total WBC (103/μL)

10 4.6

17.3 10.5

0.065

Na (mmol / L)

138.8 4.4

133.3 8.7

0.08

K (mmol /L)

4.3 0.6

4.2 0.6

0.583

Ca (mg/dl)

8.3 0.5

8.2 0.5

0.844

Cl (mmol /L)

96.6 3.6

92 6.6

0.034*

BUN (mg/dl)

25.9 16.5

32.6 12.5

0.077

Cr (mg/dl)

0.9 0.5

1.2 0.7

0.33

albumin (g/dl)

3.0 0.5

2.8 0.4

0.19

ABG on admission

pH

PCO2 (mmHg)

PO2 (mmHg)

 

7.31 0.05

70.5 12.6

48.1 13.8

 

7.34 0.10

61.5 32.0

61.5 32.0

 

0.385

0.264

0.569

 

BMI (kg/m2): body mass index (kilogram/meter2), WBC: white blood count, Na: sodium, Ca: calcium, K: potassium, Cl: chloride, BUN: blood urea nitrogen, Cr: creatinine, Y/N: yes/no,

yr: year, a: admission, ABG: arterial blood gases, PaO2 (mmHg): partial arterial pressure of oxygen, PaCO2 (mmHg): partial arterial pressure of carbon dioxide,

$: developed new consolidation on the 14th day, significance by Mann Whitney test, FEp =: Fisher's Exact test, *significant if p ≤ 0.05.