Table
3: Summary of literature review of impact
of bariatric surgery on Obstructive Sleep Apnoea (OSA).
Study |
Study design/sample size |
Weight loss procedure |
Post-op Follow-up period |
Tool to measure sleep apnoea |
Pre-procedure |
Post-procedure |
% sleep apnoea improved/ Resolved Epworth Sleepiness
Score |
||
BMI kg/m2 (range) |
AHI |
BMI kg/m2 (range) |
AHI |
||||||
A
Rao, et al. [28] |
prospective/n
= 75 |
LAGB* |
12
to 40 months |
Sleep
study |
45.2
(33-60) |
38.11
(16.6-137.7) |
30
(23-40.3) |
13.18
(0.6-91.7) |
78%
resolved |
Charuzi, et al. [29] |
Retrospective/n
= 47 |
RYGB* VBG* |
12
to 84 months |
Technion sleep questionnaire,
Sleep study |
NS* |
60.8
± 35.5 |
NS* |
8.0
± 11.8 |
72%
improved/40% resolved |
Poitou,
et al. [30] |
Prospective/n
= 35 |
RYGB* Gastric
banding |
12
months |
Sleep
study |
51.3
± 1.4 |
24.5
± 2.7 |
39.9
± 1.3 |
9.7
± 1.3 |
54.3%
AHI decrease |
Cleator. et al. [31] |
Retrospective/n
= 20 |
Ileogastrostomy |
11
months |
Questionnaire |
NS* |
NS* |
42.4 |
NS* |
30%
improved/ 55%
resolved/ 15%
unchanged |
Dixon,
et al. [32] |
Prospective/n
= 25 |
LAGB* |
17.7
± 10 months |
Sleep
study, ESS*,Neck
circumference |
52.7
± 9.5 |
61.6
± 31.9 |
37.2
± 7.2 |
13.4
± 13 |
ESS* Pre
op 13 ± 7.0 Post
op 3.8 ± 3.0 |
Pillar,
et al. [33] |
Retrospective/n
= 14 |
RYGB* VBG* |
4.5
months and 7.5 years |
Sleep
study |
45
± 7.2 |
40
± 29 |
30
± 6.0 |
24
± 23 |
72.5%
AHI decrease in 4.5 months 40%
AHI decrease in 7.5 years |
Guardiano, et al. [16] |
Retrospective/n
= 8 |
RYGB* |
28
± 20 months |
Sleep
study |
49
± 12 |
55
± 31 |
34
± 12 |
41
± 33 |
75%
AHI decrease |
Haines,
et al. [34] |
Prospective/n
= 101 |
RYGB* (50%
open, 50% lap) |
11
months (6-42) |
Sleep
study, ESS* |
56
± 1 |
51
± 4 |
38
± 1 |
15
± 2 |
ESS*
Pre
op 10 ± 1 Post
op 3mo. 6 ± 1 Post
op 24mo. 4 ± 1 |
Cleophas, et al. [22] |
Prospective/n
= 223 |
RYGB* VBG* Gastric
banding |
6,
12, 24 months |
ESS*,
Short form -12 |
44.8
± 7.9 |
NS* |
28.6
± 5.5 |
NS* |
ESS*
Pre
op 7.9 ± 4.5 Post
op 6mo.5.1 ± 3.2 Post
op 12mo.5.3 ± 3.3 Post
op 18mo. 5.0 ± 3.4 Post
op 24mo. 4.8 ± 3.3 |
Kalra, et al. [35] |
Retrospective/n
= 19 |
RYGB* |
0.9
± 0.16 years |
Sleep
study |
60.3
± 2.11 |
20.5
± 6.9 |
NS* |
1.9
± 0.6 |
|
Lankford,
et al. [36] |
Retrospective/n
= 15 |
RYGB* |
12
months |
Sleep
study |
48
± 7.4 |
40
± 37.2 |
32
± 7.8 |
NS* |
18%
reduction in CPAP pressures |
Fritscher, et al. [37] |
Prospective/n
= 12 |
RYGB* |
24.2
± 6.4 months |
Sleep
study, ESS* |
51.55
± 10.1 |
46.5
(33-140) |
34.1
± 8.1 |
16
(0.9-87) |
50%
improved/25% resolved |
Marti-valeri, et al. [38] |
Prospective/n
= 30 |
RYGB* |
12
months |
Sleep
study |
56.53
± 8.39 |
63.59
± 38.39 |
32.12
± 5.9 |
17.45
± 16.64 |
|
Lettieri, et al. [24] |
Prospective/n
= 24 |
Gastric
banding |
12
months |
Sleep
study |
51
± 10.4 |
47.9
± 33.8 |
32.1
± 5.5 |
24.5
± 18.1 |
4%
resolved |
Rasheid, et al. [17] |
Prospective/n
= 11 |
RYGB* |
3-21
months |
Sleep
study, ESS* |
62
± 3 |
56
± 13 |
40
± 2 |
23
± 7 |
ESS* Pre
op 14 ± 2 Post
op 3 ± 1 |
Scheuller and Wieder,
[18] |
Retrospective/n
= 15 |
BPD* VBG* |
12-144
months |
Sleep
study |
NS* |
96.9 |
NS
|
11.3 |
60%
resolved |
Simard, et al. [39] |
Prospective/n
= 30 |
BPD-DS* |
24
months |
Questionnaire |
56.5
± 2.3 |
NS* |
NS* |
NS* |
100%
improved |
Sugerman, et al. [40] |
Retrospective/n
= 40 |
VBG* RYGB* HG* |
69.6
± 28.8 months |
Sleep
study |
58
± 13 |
64
± 39 |
38
± 9 |
26
± 26 |
|
Valencia-Flores,
et al. [23] |
Retrospective/n
= 28 |
RYGB* VBG* |
14
months |
Sleep
study, Neck circumference |
56.5
± 12.3 |
53.7
± 46.9 |
39.2
± 8.5 |
13.7 |
46.6%
resolved |
Valera,
et al. [41] |
Prospective/n
= 56 |
RYGB* |
12
months |
Sleep
study, ESS* |
49
± 9 |
35
± 10 |
NS* |
NS* |
73%
resolved ESS* Pre
op 13.7 ± 5.5 Post
op 1 mo. 5.3 ± 4.0 |
*LAGB = Laparoscopic Adjustable Gastric
Banding, *RYGB = Roux-en-Y Gastric Bypass, *VBG =
Vertical Banded Gastroplasty, *BPD-DS = Bilio-Pancreatic Diversion-Duodenal Switch, *BPD
= Bilio-Pancreatic Diversion, *ESS =
Epworth Sleepiness Score, *HG = Horizontal Gastroplasty,
*NS = Not Specified