Table 3: Changes in spirometry parameters during the intervention.
Variable | Atorvastatin group | Placebo group | p Within group | p Between group | ||
Before | After | Before | After | |||
FVC mean | 2.27 ± 0.77 | 2.75 ± 0.26 | 2.88 ± 1.55 | 2.87 ± 0.53 | 0.11 | 0.05 |
FVC predicted% | 74.60 ± 20.82 | 89.63 ± 0.47 | 80.47 ± 29.36 | 90.56 ± 11.62 | 0.50 | 0.33 |
FEV1 mean | 1.39 ± 0.59 | 1.55 ± 0.16 | 1.67 ± 1.06 | 1.62 ± 0.41 | 0.29 | 0.20 |
FEV1 predicted% | 57.61 ± 21.38 | 63.52 ± 0.75 | 64.30 ± 32.55 | 64.00 ± 11.49 | 0.40 | 0.37 |
FEV1/FVC | 61.02 ± 13.57 | 57.04 ± 1.10 | 61.27 ± 12.44 | 57.17 ± 7.38 | 0.97 | 0.93 |
MMEF‡ | 0.68(0.74) | 0.88 ± 0.10 | 0.77(0.89) | 0.92 ± 0.28 | 0.45 | 0.31 |
MMEF predicted%‡ | 32.90(29.90) | 32.75 ± 1.62 | 27.25(38.80) | 33.47 ± 7.96 | 0.66 | 0.56 |
FEV1: Forced Expiratory Volume in the first minute; FVC: Forced Vital Capacity; MMEF: Maximum Mid expiratory Flow.
‡Median and interquartile range (IQR) were shown.