Table 2: Human
Clinical Trials using MSC in IPF (https://clinicaltrials.gov).
|
Study name |
Method of
administration and type of transplanted cells
|
Phase |
Status |
|
Study of Autologous Mesenchymal Stem Cells to Treat Idiopathic
Pulmonary Fibrosis (NCT01919827) |
Endobronchial infusion of
autologous MSC derived from bone marrow |
1 |
Recruiting participants |
|
Evaluate Safety and Efficacy of Intravenous
Autologous AD-MSC for Treatment of Idiopathic Pulmonary Fibrosis (NCT02135380) |
Intravenous autologous
Stromal Vascular Fraction Intravenous autologous adipose-derived MSC |
1 2 |
Recruiting participants |
|
A Phase I Study to Evaluate the Potential
Role of Mesenchymal Stem Cells in the Treatment of Idiopathic Pulmonary Fibrosis
(NCT01385644) [94] |
Intravenous infusion of allogenic placental
MSC |
1 |
Completed |
|
Safety and Efficacy of Allogeneic
Mesenchymal Stem Cells in Patients With Rapidly Progressive Interstitial Lung
Disease (NCT02594839) |
Intravenous infusion of allogenic bone
marrow MSC |
1 |
Recruiting participants |
|
Allogeneic Human Cells (hMSC) in Patients
With Idiopathic Pulmonary Fibrosis Via Intravenous Delivery (AETHER) (NCT02013700) |
Intravenous allogeneic adult human MSC |
1 |
Ongoing, but not recruiting participants |