Table 1: Summary of fetal progenitors, adult active and reserve stem cells markers and characteristics in small intestine and stomach.

Small Intestine
Cell type	Location	Signaling pathways involved	Marker	Full name	Ref.
CBC Active ASC	Bottom crypts between Paneth cells (position +1-4)	Canonical Wnt (ON), EGF (ON), BMP (OFF), Notch (ON), Insulin/IGF1 (ON)	Lgr5/GPR49	Leucine-rich repeat-containing G-protein coupled receptor 5	[1,10,22,35,6,38,45]
			Ascl2	Achaete-Scute Family BHLH Transcription Factor 2	[2,3]
			Smoc2	SPARC Related Modular Calcium Binding 2	[2,3]
			Olfm4	Olfactomedin 4	[2,3]
			Tnfrsf19	Tumor Necrosis Factor Receptor Superfamily, Member 19	[2,3]
			Sox9^Low	SRY (Sex Determining Region Y)-Box 9	[4]
			Msi^Low	Musashi RNA-binding protein 1	[5]
LRC Reserve ASC	Crypts above Paneth cells (position +4)	Canonical Wnt (OFF), EGF (ON), BMP (ON), Notch (ON), PTEN (ON), Insulin/IGF1 (OFF)	Bmi	Bmi1 polycomb ring finger oncogene	[6,10,34,36, 38,44]
			Hopx	HOP homeobox	[8]
			Tert	Telomerase reverse transcriptase	[7]
			Lrig1	Leucine-rich repeats and immunoglobulin-like domains 1	[9]
			Sox9^High	SRY (Sex Determining Region Y)-Box 9	[4,45]
			Msi1^High	Musashi RNA-binding protein 1	[5]
Fetal progenitor	E14-P0 epithelium	Canonical Wnt (OFF), non-Canonical Wnt (ON), EGF (ON), BMP (OFF), Notch (ON), Areg/Ereg (ON)	Trop2/ Tacstd2	Tumor-associated calcium signal transducer 2	[27]
Stomach
Cell type	Location	Signaling pathways involved	Marker	Full name	Ref.
Active ASC	Bottom antral glands (position +1-4)	Canonical Wnt (ON), EGF (ON), BMP (OFF), FGF (ON), Notch (ON), Gastrin (ON)	Lgr5/ GPR49	Leucine-rich repeat-containing G-protein coupled receptor 5	[13]
Active Stem/ Progenitor cell	Corpus glands (isthmus)	Not studied	TFF2	Trefoil factor 2	[12]
ASC	Corpus and antral glands	Not studied	Sox2	SRY (sex determining region Y)-box 2	[17]
Active progenitor cell	Antral glands (position +2-6)	Canonical Wnt (OFF), progastrin (ON)	Cck2r	Cholecystokinin B receptor	[18,19]
Dormant reserve cells	Antral glands	INFgamma	Vil1	Villin 1	[46]
Fetal progenitor Adult regeneration	E14-P0 epithelium Adult epithelium	Canonical Wnt (OFF), Areg/Ereg (ON), Notch (ON)	Trop2/ Tacstd2	Tumor-associated calcium signal transducer 2	[16]

ASC: Adult stem cells; CBC: Crypt base columnar cells; LRC: Label retaining cells; Areg: Amphiregulin; BMP: Bone morphogenetic proteins; EGF: Epidermal growth factor; Ereg: Epiregulin; FGF: Fibroblast growth factor; IFN: Interferon; IGF: Insulin growth factor; E14: Murine embryonic stage day 14; P0: Mice birth