Table 5: Bone mineral density (g/cm3) for V1, V2, and V3.
|
|
Group |
AT |
PRIME |
p-values |
||||||||
|
|
|
|
V1 |
V2 |
V3 |
V1 |
V2 |
V3 |
Time Effect |
Grp*Time |
Grp Diff for Δ V2-V1 |
Grp Diff for Δ V3-V1 |
|
Arms |
Mean |
|
0.76a |
0.74 |
0.75 |
0.76a |
0.75 |
0.75 |
0.12 |
0.40 |
0.19 |
0.74 |
|
|
95% CI |
LB |
0.76 |
0.73 |
0.73 |
0.76 |
0.74 |
0.73 |
|
|
|
|
|
|
|
UB |
0.76 |
0.75 |
0.76 |
0.76 |
0.77 |
0.76 |
|
|
|
|
|
Ribs |
Mean |
|
0.68a |
0.69 |
0.68 |
0.68a |
0.70 |
0.71 |
0.005 |
0.06 |
0.28 |
0.05 |
|
|
95% CI |
LB |
0.68 |
0.68 |
0.66 |
0.68 |
0.69 |
0.69 |
|
|
|
|
|
|
|
UB |
0.68 |
0.71 |
0.70 |
0.68 |
0.72 |
0.73 |
|
|
|
|
|
Thoracic |
Mean |
|
0.97a |
1.00 |
0.98 |
0.97a |
1.00 |
1.04 |
0.11 |
0.003 |
0.62 |
0.007 |
|
|
95% CI |
LB |
0.97 |
0.97 |
0.95 |
0.97 |
0.96 |
1.01 |
|
|
|
|
|
|
|
UB |
0.97 |
1.03 |
1.01 |
0.97 |
1.03 |
1.08 |
|
|
|
|
|
Lumbar |
Mean |
|
1.05a |
1.05 |
1.05 |
1.05a |
1.09 |
1.09 |
0.69 |
0.03 |
0.18 |
0.05 |
|
|
95% CI |
LB |
1.05 |
1.03 |
1.02 |
1.05 |
1.06 |
1.06 |
|
|
|
|
|
|
|
UB |
1.05 |
1.08 |
1.08 |
1.05 |
1.12 |
1.12 |
|
|
|
|
|
Pelvis |
Mean |
|
1.12a |
1.20 |
1.21 |
1.12a |
1.20 |
1.22 |
0.04 |
0.73 |
0.62 |
0.38 |
|
|
95% CI |
LB |
1.12 |
1.18 |
1.20 |
1.12 |
1.18 |
1.21 |
|
|
|
|
|
|
|
UB |
1.12 |
1.21 |
1.23 |
1.12 |
1.22 |
1.25 |
|
|
|
|
|
Legs |
Mean |
|
1.20a |
1.19 |
1.18 |
1.20a |
1.20 |
1.20 |
0.60 |
0.33 |
0.49 |
0.31 |
|
|
95% CI |
LB |
1.20 |
1.18 |
1.17 |
1.20 |
1.18 |
1.18 |
|
|
|
|
|
|
|
UB |
1.20 |
1.20 |
1.21 |
1.20 |
1.22 |
1.21 |
|
|
|
|
|
BMDcore |
Mean |
|
3.90a |
3.93 |
3.92 |
3.90a |
3.99 |
4.07 |
0.23 |
0.0001 |
0.20 |
0.001 |
|
|
95% CI |
LB |
3.90 |
3.88 |
3.87 |
3.90 |
3.93 |
4.04 |
|
|
|
|
|
|
|
UB |
3.90 |
3.98 |
3.97 |
3.90 |
4.01 |
4.13 |
|
|
|
|
Abbreviations: Grp = Group; Diff = Difference; CI-Confidence Interval; V1 = Visit 1; V1 = Visit 1; V2 = Visit 2; V3 = Visit 3; Δ = Change score; LB = Lower Bound; UB = Upper Bound; BMD = Bone Mineral Density