Table 5: Bone mineral density (g/cm3) for V1, V2, and V3.

 

Group

 

AT

PRIME

p-values

 

 

 

V1

V2

V3

V1

V2

V3

Time Effect

Grp*Time

Grp Diff for

Δ V2-V1

Grp Diff for Δ V3-V1

Arms

Mean

 

0.76a

0.74

0.75

0.76a

0.75

0.75

0.12

0.40

0.19

0.74

 

95% CI

LB

0.76

0.73

0.73

0.76

0.74

0.73

 

 

 

 

 

 

UB

0.76

0.75

0.76

0.76

0.77

0.76

 

 

 

 

Ribs

Mean

 

0.68a

0.69

0.68

0.68a

0.70

0.71

0.005

0.06

0.28

0.05

 

95% CI

LB

0.68

0.68

0.66

0.68

0.69

0.69

 

 

 

 

 

 

UB

0.68

0.71

0.70

0.68

0.72

0.73

 

 

 

 

Thoracic

Mean

 

0.97a

1.00

0.98

0.97a

1.00

1.04

0.11

0.003

0.62

0.007

 

95% CI

LB

0.97

0.97

0.95

0.97

0.96

1.01

 

 

 

 

 

 

UB

0.97

1.03

1.01

0.97

1.03

1.08

 

 

 

 

Lumbar

Mean

 

1.05a

1.05

1.05

1.05a

1.09

1.09

0.69

0.03

0.18

0.05

 

95% CI

LB

1.05

1.03

1.02

1.05

1.06

1.06

 

 

 

 

 

 

UB

1.05

1.08

1.08

1.05

1.12

1.12

 

 

 

 

Pelvis

Mean

 

1.12a

1.20

1.21

1.12a

1.20

1.22

0.04

0.73

0.62

0.38

 

95% CI

LB

1.12

1.18

1.20

1.12

1.18

1.21

 

 

 

 

 

 

UB

1.12

1.21

1.23

1.12

1.22

1.25

 

 

 

 

Legs

Mean

 

1.20a

1.19

1.18

1.20a

1.20

1.20

0.60

0.33

0.49

0.31

 

95% CI

LB

1.20

1.18

1.17

1.20

1.18

1.18

 

 

 

 

 

 

UB

1.20

1.20

1.21

1.20

1.22

1.21

 

 

 

 

BMDcore

Mean

 

3.90a

3.93

3.92

3.90a

3.99

4.07

0.23

0.0001

0.20

0.001

 

95% CI

LB

3.90

3.88

3.87

3.90

3.93

4.04

 

 

 

 

 

 

UB

3.90

3.98

3.97

3.90

4.01

4.13

 

 

 

 

Abbreviations: Grp = Group; Diff = Difference; CI-Confidence Interval; V1 = Visit 1; V1 = Visit 1; V2 = Visit 2; V3 = Visit 3; Δ = Change score; LB = Lower Bound; UB = Upper Bound; BMD = Bone Mineral Density