Total number of patients 690 (percentage)

Mean time (IQR)

p-value

Age

18-82 (Mean 44)

0.0745

Gender

Male

89 (13%)

102 (70-120)

Female

601

87 (60-109)

0.0003

BMI

16.4-58.8 (Mean 32.6)

0.2212

Comorbidities

Yes

315

88 (60-110)

No

375

91 (65-115)

0.289

Procedure timing

Elective

491

86 (60-105)

Same admission

199

96 (70-120)

0.0017

Hospital

GSH

253

95 (70-120)

0.0007

MPH

240

85 (60-105)

0.0275

VH

63

88 (60-110)

0.8703

NSH

134

85 (60-100)

0.1752

0.0074 (ANOVA)

Indications

Biliary colic

246

78 (60-90)

< 0.0001

Cholecystitis

204

92 (65-120)

0.1337

Choledocholithiasis

120

107 (70-130)

< 0.0001

Gallstone pancreatitis

108

89 (61-120)

0.9301

others

12

75 (50-101)

0.1770

< 0.0001 (ANOVA)

Surgeon

Senior

408

94 (60-120)

Junior

282

82 (60-95)

< 0.0001

Assistant

Senior

271

89 (63-110)

Junior

419

89 (60-115)

0.9971

Critical view of safety

Yes

624

86 (60-107)

No

66

117 (85-150)

< 0.0001

Expected difficult GB

Yes

189

102 (72-120)

No

501

84 (60-100)

< 0.0001

Difficult

abdomen access

Yes

58

113 (77-141)

No

632

87 (60-110)

< 0.0001

IOC performed

Yes

117

109 (90-120)

No

573

82 (60-100)

< 0.0001

Gallstone spillage

Yes

137

104 (75-120)

No

553

86 (60-105)

< 0.0001

Bile leak

Yes

298

99 (72-120)

No

392

81 (60-93)

< 0.0001

Estimated blood loss

Minimal

639

86 (60-102)

< 0.0001

Moderate

50

128 (100-141)

< 0.0001

Severe

1

158

0.0626