Table 1: Patient
and tumour characteristics of the study patients.
|
Laparoscopic (n) =
64 |
Open (n) = 64 |
p-value
|
Age - median (range) |
68 (39-93) |
70 (43-88) |
0.949 |
Female gender - n (%) |
28 (44 %) |
24 (38 %) |
0.472 |
Clinical Risk Score - median
(range) |
2 (0-3) |
2 (0-4) |
|
CRS 0 - n (%) |
2 (3 %) |
3 (5 %) |
|
CRS 1 - n (%) |
24 (37 %) |
18 (28 %) |
|
CRS 2 - n (%) |
28 (44 %) |
34 (53 %) |
|
CRS 3 - n (%) |
10 (16 %) |
7 (11 %) |
|
CRS 4 - n (%) |
0 (0 %) |
2 (3 %) |
0.384 |
Positive lymph node of primary - n
(%) |
42 (66 %) |
44 (69 %) |
0.710 |
Disease free < 1 year - n (%) |
42 (66 %) |
40 (63 %) |
0.713 |
Preoperative CEA - Median |
< 5 |
< 5 |
|
> 200 ng/ml - n (%) |
1 (2 %) |
1 (2 %) |
1. |
No. of hepatic tumours median (range) |
1 (1-4) |
1 (1-3) |
0.529 |
≥ 2 -
n (%) |
9 (14 %) |
12 (19 %) |
0.474 |
Tumor size (mm) - median (range) |
22 (6 - 65) |
25 (5 - 60) |
0.265 |
Extrahepatic
disease present* - n (%) |
10 (16 %) |
7 (11 %) |
0.435 |
Prior liver surgery - n (%) |
5 (8 %) |
5 (8 %) |
1. |
Type of prior: Percutanous/lap./open |
3/1/1. |
2/0/3. |
|
CCI (range) |
(0-4) |
(0-4) |
|
≤ 1 -
n (%) |
60 (94 %) |
60 (94 %) |
|
≥ 2 -
n (%) |
4 (6 %) |
4 (6 %) |
1. |
No. of segments involved |
|
||
One segment** - n (%) |
39 (61 %) |
46 (72 %) |
|
Two segments*** - n (%) |
25 (39 %) |
18 (28 %) |
0.190 |
Tumor location |
|
||
Anterolateral segments 2, 3, 4b, 5 or 6 - n (%) |
61 (95 %) |
45 (70 %) |
|
Posterosuperior segments 4a, 7 or 8 - n (%) |
3 (5 %) |
19 (30 %) |
< 0.001 |
*In both groups all cases of extrahepatic
disease was due to resectable lungmetastases.
**Wedge resections and monosegmentectomies
***Anatomical bisegmentectomies
and non-anatomical resections in two segments
CCI: charlson comorbidity index;
CRS: clinical risk score proposed by Fong.