Table 1: Patient and tumour characteristics of the study patients.

 

 

Laparoscopic (n) = 64 

Open (n) = 64

p-value

Age - median (range)

68 (39-93)

70 (43-88)

0.949

Female gender - n (%)

28 (44 %)

24 (38 %)

0.472

Clinical Risk Score - median (range)

2 (0-3)

2 (0-4)

 

CRS 0 - n (%)

2 (3 %)

3 (5 %)

 

CRS 1 - n (%)

24 (37 %)

18 (28 %)

 

CRS 2 - n (%)

28 (44 %)

34 (53 %)

 

CRS 3 - n (%)

10 (16 %)

7 (11 %)

 

CRS 4 - n (%)

0 (0 %)

2 (3 %)

0.384

Positive lymph node of primary - n (%)

42 (66 %)

44 (69 %)

0.710

Disease free < 1 year - n (%)

42 (66 %)

40 (63 %)

0.713

Preoperative CEA - Median

< 5

< 5

 

  > 200 ng/ml - n (%)

1 (2 %)

1 (2 %)

1.

No. of hepatic tumours  median (range)

1 (1-4)

1 (1-3)

0.529

  2  - n (%)

9 (14 %)

12 (19 %)

0.474

Tumor size (mm) - median (range)

22 (6 - 65)

25 (5 - 60)

0.265

Extrahepatic disease present* - n (%)

10 (16 %)

7 (11 %)

0.435

Prior liver surgery - n (%) 

5 (8 %)               

5 (8 %)           

1.

  Type of prior: Percutanous/lap./open

3/1/1.

2/0/3.

 

CCI  (range)

(0-4)

(0-4)

 

  1  - n (%)

60 (94 %)

60 (94 %)

 

  2  - n (%)

4 (6 %)

4 (6 %)

1.

No. of segments involved

 

  One segment** - n (%)

39 (61 %)

46 (72 %)

 

  Two segments*** - n (%)

25 (39 %)

18 (28 %)

0.190

Tumor location

 

  Anterolateral segments 2, 3, 4b, 5 or 6 - n (%)

61 (95 %)

45 (70 %)

 

  Posterosuperior segments 4a, 7 or 8 - n (%)

3 (5 %)

19 (30 %)

< 0.001

 

*In both groups all cases of extrahepatic disease was due to resectable lungmetastases.

**Wedge resections and monosegmentectomies

***Anatomical bisegmentectomies and non-anatomical resections in two segments

CCI: charlson comorbidity index; CRS: clinical risk score proposed by Fong.