Table 4: Performance of the techniques on clinical forms and categories of the disease.
|
|
Nested IS2404 PCR |
Conventional IS2404 PCR |
BU-LAMP |
|
||||
|
|
Positive n (%) |
Negative n (%) |
Positive n (%) |
Negative n (%) |
Positive n (%) |
Negative n (%) |
x2 (p-value) |
|
|
Clinical forms of lesions |
|
|
|
|
|
|
|
|
|
Ulcer (n = 103) |
89 (86.4%)* |
14 (13.6%) |
74 (71.8%) |
29 (28.2%) |
89 (86.4%)* |
14 (13.6%) |
9.68 (0.008) |
|
|
Nodule (n = 23) |
20 (87.0%) |
3 (13.0%) |
17 (74.0%) |
6 (26.0%) |
20 (87.0%) |
3 (13.0%) |
1.81 (0.403) |
|
|
Oedema (n = 15) |
13 (86.7%) |
2 (13.3%) |
13 (86.7%) |
2 (13.3%) |
10 (66.7%) |
5 (33.3%) |
2.50 (0.286) |
|
|
Categorization of lesions |
|
|
|
|
|
|
|
|
|
Category 1 (n = 64) |
58 (90.6) |
6 (9.4%) |
55 (86.0%) |
9 (14.0%) |
58 (90.6%) |
6 (9.7%) |
0.96 (0.618) |
|
|
Category II (n = 24) |
21 (87.5)* |
3 (12.5%) |
13 (54.2%) |
11 (45.8%) |
21 (87.5%)* |
3 (12.5%) |
6.82 (0.033) |
|
|
Category III (n = 53) |
43 (81.1) |
10 (18.9%) |
36 (67.9%) |
17 (23.1%) |
40 (75.5%) |
13 (24.5%) |
2.47 (0.290) |
|