Effect of chlorpyrifos (1/10 LD50, 33.3 mg kg-1 body weight) on serum urea and creatinine levels in male domestic rabbits.

Table 6: Effect of chlorpyrifos (1/10 LD50, 33.3 mg kg-1 body weight) on serum urea and creatinine levels in male domestic rabbits.

Parameter	Treatment	Experimental period (weeks)
Parameter	Treatment	1	2	3	4	5	6
Urea (mg/dl)	Control	38.7 ± 2.1	37.4 ± 1.9	37.5 ± 2.2	36.6 ± 1.8	35.8 ± 1.9	37.1 ± 2.3
	Chlorpyrifos	43.5 ± 2.6	43.1 ± 2.3	45.8 ± 2.5	49.4 ± 2.4	54.3 ± 3.1	57.8 ± 3.0
	p-value	0.208	0.109	0.047	0.013	0.007	0.002
Creatinine (mg/dl)	Control	0.63 ± 0.02	0.65 ± 0.02	0.70 ± 0.04	0.69 ± 0.03	0.67 ± 0.04	0.64 ± 0.02
	Chlorpyrifos	0.69 ± 0.04	0.75 ± 0.06	0.79 ± 0.05	0.90 ± 0.07	0.81 ± 0.05	0.73 ± 0.04
	p-value	0.209	0.091	0.183	0.018	0.049	0.096

The number of animals was 6 per time interval for each control and chlorpyrifos-treated rabbits. All values are expressed as mean ± SEM. p < 0.05: significant.