Table 8: Effect of chlorpyrifos (1/10 LD50, 33.3 mg kg-1 body weight) on serum calcium and phosphorus concentrations in male domestic rabbits.
Parameter |
Treatment |
Experimental period (weeks) |
|||||
1 |
2 |
3 |
4 |
5 |
6 |
||
Calcium (mg/dl) |
Control |
14.1 ± 0.4 |
13.8 ± 0.2 |
14.2 ± 0.5 |
13.6 ± 0.3 |
13.9 ± 0.4 |
14.0 ± 0.6 |
Chlorpyrifos |
14.9 ± 0.6 |
15.3 ± 0.7 |
16.0 ± 0.7 |
16.1 ± 1.0 |
16.0 ± 0.6 |
15.8 ± 0.5 |
|
p-value |
0.325 |
0.104 |
0.082 |
0.034 |
0.046 |
0.073 |
|
Phosphorus (mg/dl) |
Control |
7.3 ± 0.4 |
7.5 ± 0.3 |
7.1 ± 0.3 |
7.4 ± 0.2 |
7.5 ± 0.4 |
7.3 ± 0.3 |
Chlorpyrifos |
6.9 ± 0.2 |
6.5 ± 0.2 |
6.3 ± 0.1 |
6.7 ± 0.3 |
6.7 ± 0.1 |
6.4 ± 0.1 |
|
p-value |
0.331 |
0.032 |
0.065 |
0.096 |
0.088 |
0.047 |
The number of animals was 6 per time interval for each control and chlorpyrifos-treated rabbits. All values are expressed as mean ± SEM. p < 0.05: significant.