Table 8: Effect of chlorpyrifos (1/10 LD50, 33.3 mg kg-1 body weight) on serum calcium and phosphorus concentrations in male domestic rabbits.

 

Parameter

 

Treatment

Experimental period (weeks)

1

2

3

4

5

6

Calcium

(mg/dl)

Control

14.1 ± 0.4

13.8 ± 0.2

14.2 ± 0.5

13.6 ± 0.3

13.9 ± 0.4

14.0 ± 0.6

Chlorpyrifos

14.9 ± 0.6

15.3 ± 0.7

16.0 ± 0.7

16.1 ± 1.0

16.0 ± 0.6

15.8 ± 0.5

p-value

0.325

0.104

0.082

0.034

0.046

0.073

Phosphorus

(mg/dl)

Control

7.3 ± 0.4

7.5 ± 0.3

7.1 ± 0.3

7.4 ± 0.2

7.5 ± 0.4

7.3 ± 0.3

Chlorpyrifos

6.9 ± 0.2

6.5 ± 0.2

6.3 ± 0.1

6.7 ± 0.3

6.7 ± 0.1

6.4 ± 0.1

p-value

0.331

0.032

0.065

0.096

0.088

0.047

The number of animals was 6 per time interval for each control and chlorpyrifos-treated rabbits. All values are expressed as mean ± SEM. p < 0.05: significant.