Table 2: Clinicals signs in subacute oral toxicity test.

Doses (mg/kg)

Observe design of toxicity

Control (G1)

No signs of toxicity

No death

50 (G2)

No signs of toxicity

No death

100 (G3)

No signs of toxicity

No death

500 (G4)

Loss of appetite, poor digestibility, black hard faeces, runny nose, excitation, convulsions, lethargy, mortality

1000 (G5)

Loss of appetite, poor digestibility, black hard faeces, runny nose, self-injury, excitation, lethargy, convulsions, mortality