Alterations in the liver weight, body weight and coefficient of liver weights with the CeO2 nanoparticle exposure.

Table 1: Alterations in the liver weight, body weight and coefficient of liver weights with the CeO2 nanoparticle exposure.

Liver tissues collected from animal groups that were intratracheal instilled with either normal saline or CeO₂ nanoparticles at a dosage of 7.0 mg/kg after 1, 3, 14, 28, 56 and 90 days post exposure, and cleaned to remove blood and tissue debris with Krebs's lactate solution and weighed immediately (N = 6/group).

Days of Exposure	Body weight		Liver weight		Coefficient of liver weight to body weight
	Saline control	Ceo₂-7.0 mg/kg	Saline control	Ceo₂-7.0 mg/kg	Saline control	Ceo₂-7.0 mg/kg
1	319.67 ± 15.92	319.67 ± 15.20	13.18 ± 0.68	13.00 ± 1.05	41.27 ± 2.2	40.61 ± 2.34
3	310.33 ± 28010	331.67 ± 24	12.27 ± 1.58	11.85 ± 1.06	39.44 ± 1.86	35.85 ± 3.7^*
14	345.67 ± 27.11	332.33 ± 21.07	13.31 ± 2.00	13.31 ± 2.00	38.40 ± 3.80	38.04 ± 4.05
28	411.33 ± 29.2^*µ	403.67 ± 28.94^*µ	15.00 ± 0.80^α	14.70 ± 1.55^α	36.60 ± 2.64^*	36.30 ± 1.88^*
56	451.67 ± 26.21^*αµ	451.33 ± 34.6^*αµ¶	15.34 ± 1.30^α	15.34 ± 1.30^α	33.96 ± 2.02^*	33.55 ± 2.69^*¶
90	523.33 ± 60.87^*αµ¶#	519.33 ± 44.84^*αµ¶#	17.56 ± 2.35^*αµ	17.06 ± 1.80^*αµ	33.60 ± 2.62^*	32.82 ± 1.45^*¶

^*Significant different from the 1 Day exposure group in each condition; ^αSignificant different from the 3 Day exposure group in each condition; ^µSignificant different from the 14 Day exposure group in each condition; ^¶Significant different from the 28 days exposure group; ^#Significant different from the 56 days exposure group.