Table 1: Demographic Characteristics and Clinical Data

Study cohort No CMV events CMV events
N = 139 N = 76 N = 63
Age (years)
Mean SD 49.8 12.64
Sex (male) 83 (60%) 47 (62%) 36 (57%)
Underlying disease
Idiopathic pulmonary fibrosis 59 (42.4%) 33 (43%) 26 (40%)
Chronic obstructive pulmonary disease 35 (25.2%) 17 (22%) 18 (28%)
Cystic fibrosis 14 (10%) 11 (14%) 3 (5%)
Miscellaneous 31 (22.4%) 15 (21%) 16 (25%)
Types of transplant
Single lung 96 (69%) 49 (64%) 46 (73%)
Double lung 43 (31%) 26 (36%) 17 (27%)
Duration of prophylaxis (months) Median (min. - max.) 4 (1.5 - 9)
Donor/receptor serological status
CMV D+/R- 15 (10.7%) 6 (8%) 9 (14%)
CMV D-/R- 16 (11.5%) 13 (17%) 3 (5%)
CMV D-/R+ 25 (18%) 17 (22%) 8 (13%)
CMV D+/R+ 83 (57%) 40 (53%) 43 (68%)
Rejection requiring increased immunosuppression 47 (34%) 26 (34%) 21(33%)


CMV: Cytomegalovirus, R: Receptor, D: Donor