| Profiles | Description |
| INTERMACS 1 | Hemodynamic instability in spite of increasing doses of catecholamines and/or mechanical circulatory support with critical hypo-perfusion of target organs (severe cardiogenic shock) |
| INTERMACS 2 | Intravenous inotropic support with acceptable blood pressure, but rapid deterioration of kidney function, nutritional state, or signs of congestion |
| INTERMACS 3 | Hemodynamic stability with low or intermediate, but necessary due to hypotesion, doses of inotropics, worsening of symptoms, or progressive kidney failure |
| INTERMACS 4 | Temporary cessation of inotropic treatment is possible, but the patient presents frequent symptom recurrences and typically with fluid overload |
| INTERMACS 5 | Complete cessation of physical activity, stable at rest, but frequently with moderate water retention and some level of kidney dysfunction |
| INTERMACS 6 | Minor limitation on physical activity and absence of congestion while at rest. Easily fatigued by light activity |
| INTERMACS 7 | Patient in NYHA functional class II or III with no current or recent unstable water balance |