Table 4: Comparison of demographic, pre-operative, operative, post-operative and donor data between patient with and those without infection during the first post-operative month.

 

 

Non infection

(n = 4 )

Infection

(n = 22 )

P-value

(univariate)

P-value

(multivariate)

Demographic data of recipient

 

 

 

 

Gender:

Male

Female

 

3 (23.1)

1 (7.7)

 

10 (76.9)

12 (92.3)

 

0.6

 

NS

 

Age

3.7 ± 5.5

5.8 ± 5.6

0.1

NS

Pre-LTx data

 

 

 

 

Pre-LTx infection

3 (75)

11 (50)

0.7

NS

 Pre-LTx steroid therapy

0.0

1 (4.5)

1

NS

Prior abdominal surgery

1 (25)

5 (22.7)

1

NS

Growth failure

3 (75)

10 (45.5)

0.6

NS

Donor data

 

 

 

 

Age of the donor

25.5 ± 3.7

33.2 ± 4.4

0.005*

NS

BMI

21.4 ± 1.3

26.4 ± 3.9

0.016*

NS

Surgical data

 

 

 

 

Type of anastomosis of HA:

End to end

 

4 (100)

 

22 (100)

 

--

 

Type of anastomosis of bile duct: (n = 18)

Duct to duct

Roux-en-y

 

 

1 (33.3)

2 (66.7)

 

 

3 (20)

12 (80)

 

 

1

 

 

NS

 

Surgical re-exploration

0.0

2 (9.1)

1

NS

Cold ischemia time (minutes)

49.2 ± 33.6

61.7 ± 25.6

0.7

NS

 

Warm ischemia time (minutes)

36 ± 6.37

40.6 ± 12.5

0.6

NS

 

Anhepatic phase (minutes)

11 ± 1.4

75.7 ± 45.3

0.03*

NS

 

Period of the operation (hours)

9.8 ± 1.13

10.1 ± 2

0.55

NS

 

Post-LTx Immunosuppressant

 

 

 

 

Starting dose: (n = 25)

Average

Low

High

 

3 (100)

0.0

0.0

 

10 (45.5)

9 (40.9)

3 (13.6)

 

 

0.2

 

 

NS

 

Starting time: (n = 25)

 The day before LTx

 The day after LTx

 2 days after LTx

 3 days after LTx

 

2 (66.7)

1 (33.3)

0.0

0.0

 

14 (63.7)

6 (27.3)

1 (4.5)

1 (4.5)

 

 

0.79

 

 

 

NS

 

Post-LTx Complications

 

 

 

 

Vascular complications

2 (50)

9 (40.9)

0.6

NS

Biliary complications

1 (25)

4 (18.2)

1

NS

Rejection

0.0

4 (18.2)

0.73

NS

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

LTx (liver transplantation)

NS (not significant)