Table 4: Comparison of demographic, pre-operative, operative, post-operative and
donor data between patient with and those without infection during the first post-operative
month.
|
Non infection (n = 4 ) |
Infection (n = 22 ) |
P-value (univariate) |
P-value (multivariate) |
Demographic data of recipient |
|
|
|
|
Gender: Male Female |
3
(23.1) 1
(7.7) |
10 (76.9) 12
(92.3) |
0.6 |
NS |
Age |
3.7 ± 5.5 |
5.8 ± 5.6 |
0.1 |
NS |
Pre-LTx data |
|
|
|
|
Pre-LTx
infection |
3 (75) |
11 (50) |
0.7 |
NS |
Pre-LTx steroid therapy |
0.0 |
1 (4.5) |
1 |
NS |
Prior
abdominal surgery |
1
(25) |
5 (22.7) |
1 |
NS |
Growth
failure |
3
(75) |
10 (45.5) |
0.6 |
NS |
Donor data |
|
|
|
|
Age of the donor |
25.5 ± 3.7 |
33.2 ± 4.4 |
0.005* |
NS |
BMI |
21.4 ± 1.3 |
26.4 ± 3.9 |
0.016* |
NS |
Surgical data |
|
|
|
|
Type of anastomosis of HA: End to end |
4 (100) |
22 (100) |
-- |
|
Type of anastomosis of bile duct: (n = 18) Duct to duct Roux-en-y |
1 (33.3) 2 (66.7) |
3 (20) 12 (80) |
1 |
NS |
Surgical re-exploration |
0.0 |
2 (9.1) |
1 |
NS |
Cold
ischemia time (minutes) |
49.2
± 33.6 |
61.7
± 25.6 |
0.7 |
NS |
Warm
ischemia time (minutes) |
36
± 6.37 |
40.6
± 12.5 |
0.6 |
NS |
Anhepatic
phase (minutes) |
11
± 1.4 |
75.7
± 45.3 |
0.03* |
NS |
Period
of the operation (hours) |
9.8
± 1.13 |
10.1
± 2 |
0.55 |
NS |
Post-LTx
Immunosuppressant |
|
|
|
|
Starting
dose: (n = 25) Average Low High |
3
(100) 0.0 0.0 |
10
(45.5) 9
(40.9) 3
(13.6) |
0.2 |
NS |
Starting
time: (n = 25) The day before LTx The day after LTx 2 days after LTx 3 days after LTx |
2
(66.7) 1
(33.3) 0.0 0.0 |
14
(63.7) 6
(27.3) 1
(4.5) 1
(4.5) |
0.79 |
NS |
Post-LTx
Complications |
|
|
|
|
Vascular
complications |
2
(50) |
9
(40.9) |
0.6 |
NS |
Biliary
complications |
1
(25) |
4
(18.2) |
1 |
NS |
Rejection |
0.0 |
4
(18.2) |
0.73 |
NS |
LTx (liver transplantation)
NS (not significant)