Stable Patients (n = 10)

Patients with CAD (n = 5)

Cyclosporine dosage (mg/kg/d)

4.6 ± 1.9

4.4 ± 2.5

C₀ (ng/mL)

73.5 ± 61.4

132.5 ± 54.8

C₂ (ng/mL)

AUC (ng.h/mL)^*

501.1 ± 242.4

2868 ± 1058

692.1 ± 118.2

4380 ± 542

Acute rejection attacks (n)^*

2/10

4/5

Glomerular filtration rate (mL/min/1.73 m²)

84 ± 29

76 ± 51

Posttransplant duration (mo)

20.4 ± 22.8

34.1 ± 21.5