Table 1: Antiviral activities of herbal extracts against diverse HIV-1 primary isolates of clades A, B, and C.

 

 

 

Anti-HIV-1 titers (50% inhibition dose)1

 

Viruses

Clade

Gingseng

Salviae

Cinnamomi

Asari

Astragali

SHIV-89.6P

B

22

119

150

< 20

< 20

SF162.LS

B

< 20

129

348

< 20

< 20

6535.3

B

24

489

514

< 20

< 20

QH0692.42

B

125

433

255

< 20

< 20

SC422661.8

B

36

6,768

763

< 20

< 20

PVO.4

B

321

12,828

1,008

< 20

< 20

Du123.6

C

27

945

403

< 20

< 20

Du156.2

C

38

1,079

370

< 20

< 20

Q23.17

A

26

309

290

< 20

< 20

Q168.a2

A

20

431

298

< 20

< 20

SVA-MLV

Control

24

90

95

< 20

< 20

 

 

 

Anti-HIV-1 titers (90% inhibition dose)2

 

SHIV-89.6P

B

< 20

68

64

< 20

< 20

SF162.LS

B

< 20

62

50

< 20

< 20

6535.3

B

< 20

85

68

< 20

< 20

QH0692.42

B

< 20

74

39

< 20

< 20

SC422661.8

B

< 20

247

79

< 20

< 20

PVO.4

B

< 20

587

134

< 20

< 20

Du123.6

C

< 20

118

80

< 20

< 20

Du156.2

C

< 20

186

84

< 20

< 20

Q23.17

A

< 20

82

72

< 20

< 20

Q168.a2

A

< 20

71

63

< 20

< 20

SVA-MLV

Control

< 20

26

29

< 20

< 20

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

1Dilutions of herbal extracts at which relative luminescence units were reduced to 50% compared to virus control wells without the test sample.


2Values are the sample dilution at which relative luminescence units were reduced 90% compared to virus control wells (not containing any test sample).