Table 1: Antiviral activities of herbal
extracts against diverse HIV-1 primary isolates of clades A, B, and C.
|
|
|
Anti-HIV-1 titers (50% inhibition dose)1 |
|
||
Viruses |
Clade |
Gingseng |
Salviae |
Cinnamomi |
Asari |
Astragali |
SHIV-89.6P |
B |
22 |
119 |
150 |
< 20 |
< 20 |
SF162.LS |
B |
< 20 |
129 |
348 |
< 20 |
< 20 |
6535.3 |
B |
24 |
489 |
514 |
< 20 |
< 20 |
QH0692.42 |
B |
125 |
433 |
255 |
< 20 |
< 20 |
SC422661.8 |
B |
36 |
6,768 |
763 |
< 20 |
< 20 |
PVO.4 |
B |
321 |
12,828 |
1,008 |
< 20 |
< 20 |
Du123.6 |
C |
27 |
945 |
403 |
< 20 |
< 20 |
Du156.2 |
C |
38 |
1,079 |
370 |
< 20 |
< 20 |
Q23.17 |
A |
26 |
309 |
290 |
< 20 |
< 20 |
Q168.a2 |
A |
20 |
431 |
298 |
< 20 |
< 20 |
SVA-MLV |
Control |
24 |
90 |
95 |
< 20 |
< 20 |
|
|
|
Anti-HIV-1 titers (90% inhibition dose)2 |
|
||
SHIV-89.6P |
B |
< 20 |
68 |
64 |
< 20 |
< 20 |
SF162.LS |
B |
< 20 |
62 |
50 |
< 20 |
< 20 |
6535.3 |
B |
< 20 |
85 |
68 |
< 20 |
< 20 |
QH0692.42 |
B |
< 20 |
74 |
39 |
< 20 |
< 20 |
SC422661.8 |
B |
< 20 |
247 |
79 |
< 20 |
< 20 |
PVO.4 |
B |
< 20 |
587 |
134 |
< 20 |
< 20 |
Du123.6 |
C |
< 20 |
118 |
80 |
< 20 |
< 20 |
Du156.2 |
C |
< 20 |
186 |
84 |
< 20 |
< 20 |
Q23.17 |
A |
< 20 |
82 |
72 |
< 20 |
< 20 |
Q168.a2 |
A |
< 20 |
71 |
63 |
< 20 |
< 20 |
SVA-MLV |
Control |
< 20 |
26 |
29 |
< 20 |
< 20 |
1Dilutions of herbal extracts at which
relative luminescence units were reduced to 50% compared to virus control wells
without the test sample.
2Values are the sample dilution at which relative luminescence units
were reduced 90% compared to virus control wells (not containing any test
sample).