Table 2: Haematological and Biochemical indices of HIV seropositive participants before and after HAART exposure.
Parameter | HAART-naïve | HAART-exposed | p-value |
Haematological indices | |||
RBC (× 106 cell/µl) | 3.99 ± 1.38 | 4.36 ± 1.31 | 0.0001 |
Haemoglobin (g/dl) | 11.91 ± 3.75 | 12.94 ± 3.84 | 0.0001 |
WBC (× 109 cell/L) | 4.90 ± 1.57 | 4.97 ± 1.45 | 0.6819 |
Neutrophil (× 109 cell/L) | 2.20 ± 0.85 | 2.01 ± 0.82 | 0.1034 |
Lymphocytes (× 109 cell/L) | 2.36 ± 0.97 | 1.97 ± 0.56 | 0.0001 |
Platelets (× 109 cell/L) | 180.57 ± 1.88 | 188.86 ± 1.76 | 0.1118 |
Biochemical indices | |||
Total Protein (g/L) | 89.27 ± 17.5 | 96.72 ± 14.13 | < 0.0001 |
Albumin (g/L) | 38.76 ± 1.58 | 43.66 ± 1.35 | 0.0002 |
Aspartate transaminase (U/L) | 30.13 ± 1.77 | 30.41 ± 1.77 | 0.7962 |
Alanine transaminase (U/L) | 24.19 ± 1.83 | 26.46 ± 1.85 | 0.0456 |
Alkaline Phosphatase (U/L) | 224.48 ± 135.53 | 268.15 ± 142.63 | 0.0392 |
Urea (mmol/L) | 3.24 ± 0.54 | 3.56 ± 0.72 | 0.0117 |
Creatinine (umol/L) | 80.04 ± 29.07 | 83.49 ± 32.06 | 0.0407 |
P value was calculated by Pearson's Chi square (χ2) with confidence interval (CI) of 95% and 1 degree of freedom (df).
P values less than 0.05 were considered statistically significant and are indicated in bold fonts.
Normal reference range for Biochemical indices:
Total Protein: 60-83 g/L
Albumin: 35-55 g/L
Aspartate transaminase: 10-40 U/L
Alanine transaminase: 7-56 U/L
Alkaline Phosphatase: 44-147 U/L
Urea: 2.5 to 7.1 mmol/L
Creatinine: 45-90 µmol/L for women and 60-110 µmol/L for men.