Table 1: Correlation between various patterns of TST response and anergy testing results to recall antigens.
TST results | Anergy testing results to recall antigens (n = 7) in Multi-test CMI | |||||||||
Old Tuberculin (OT) | Other antigens (n = 6) | |||||||||
1 to 3 antigens | 4 to 6 antigens | |||||||||
Pattern | No | Pattern of results | Pattern of results | Pattern of Results | ||||||
+/+ No (%) |
-/- No (%) |
-/+ No (%) |
+/+ No (%) |
-/- No (%) |
-/+ No (%) |
+/+ No (%) |
-/- No (%) |
-/+ No (%) |
||
+/+ a | 22 | 20 (90.9)* |
2 (9.1) |
- | 18 (81.8)* |
4 (18.2) |
- | 14 (63.6)* |
7 (31.8) |
1 (4.6) |
-/- b | 72 | - | 71 (98.6)* |
1 (1.4) |
2 (2.8) |
68 (94.4)* |
2 (2.8) |
- | 71 (98.6)* |
1 (1.4) |
-/+ c | 50 | 1 (2) |
4 (8) |
45* (90) |
39 (78) |
6 (12) |
5 (10) |
25 (50) |
23 (46) |
2 (4) |
a = Positive TST both at enrollment as well as at 1yr follow up TST; b = Negative TST both at enrollment as well as at 1 yr follow up TST; c = Negative first TST but positive in second TST (boosting) at enrollment or at 1 yr follow up TST (conversion); *Agreement between TST and OT: κ values > 0.75 for all three patterns of TST response.