Table 1: Utility of various hormonal tests for primary infertility in the ovulatory patient.

UTILITY

TEST

INDICATION

HIGH Utility

Patient age

Remains the best predictor of success of pregnancy through natural conception or Assisted Reproductive Technologies

Anti-Mullerian Hormone

The most reliable screening test for poor ovarian response to ovarian stimulation

LOW Utility

Early follicular FSH with estradiol

A specific but not sensitive test of decreased ovarian reserve

Urinary LH

Useful if couple has difficulty with timing or frequency of intercourse

TSH

To rule out subclinical hypothyroidism

Thyroid antibody testing: If TSH mildly elevated

To help determine whether or not to initiate treatment in patients with subclinical hypothyroidism

Mid-luteal progesterone

Not necessary to confirm ovulation if the patient reports a history of regular and predictable menses

NO Utility

Prolactin

 

Inhibin B

Estradiol alone