Table 1: Study characteristics and outcomes.

 

Author (year)

Country& Participants

Design

Journal

J. Impact Factor.

Conclusion

Swithinbank L. (2005)

UK

N = 69

Prospective Observational

cross over study

Journal of Urology

3.746

Caffeine restriction does not improve symptoms Increased symptoms with higher fluid intake P = 0.006

Tomlinson B.U

(2009)

USA

N = 218

Quasi-expermental design

Int Urogynecology Journal

2.16

Caffeine restriction to 100 mg showed a positive relation with reduction of urinary episodes (P = 0.074)

Bryant Ch. (2002)

Australia

N = 96

RCT

British Journal

of Nursing

0.47

Significant reduction in caffeine consumption and less occasions of urgency in experimental group (P = 0.002)

Townsed M. (2012)

USA

N = 21.564

Prospective cohort

Obstetrics and Gynecolgy J.

4.73

No association with caffeine intake reduction and symptoms were Observed OR 0.87 (0.70-1.08)

Jura Y.H. (2011)

USA

N = 65.176

Prospective cohort

Journal of Urology

3.746

Incidence of urgency incontinence was associated with high intake of caffeine > 300 mg/day RR: 1,19 (1.06 - 01.34)

Arya L (2000)

USA

N = 259

Case Control

Obstetrics and Gynecology J.

4.79

Very high intake of caffeine (> 400 mg/day) was significantly associated with higher odds of detrusor instability OR 2.4 (1.1,  6.5) p = 0.006

Bradley (2005)

USA

N = 297

Longitudinal observational study

Journal of Women´s Health

0.57

Association with difficulty in emptying bladder OR 5.3 (1.2-23.0), P = 0.06

Hirayama F.

(2012)

Japan

N = 298

Cross-sectional

J Prev Med Public Health.

0.235

No association observed OR 1.12 (0.57-2.22) P = 0.44

Hannestad

(2003)

Norway

N = 27936

Cross-sectional

Int. J. of Obstetrics and

Gynecology

2.045

No association observed with coffee. OR 1.0 (0.9-1.1) Significant association with tea. OR 1.3 (1.2 -1.5)

Gleason J.

(2012)

USA

N = 4309

Cross-sectional

Int. Urogynec J.

2.16

Prevalence of any UI was associated with caffeine intake ≥ 204 mg/day (POR 1.42, 95% CI 1.07-2.07)