Table 1: Univariate analysis of the comparing of the exposed and the non-exposed groups at the end of follow-up period in relation to the study outcomes

Variable

 

Biologics use

 # 73

Non- Biologics use

# 262

OR*

95% CI**

Fisher's Exact p value P( < 0.05)

Surgery

No Surgery

20

53

37

223

2.556

1.386-4.715

 

0.0038**

Opthalmologic Sympt.

No Symptoms

1

72

0

260

12.81

0.516-317.9

 

0.19

Dermatologic/Oral Sympt.

No Symptoms

3

70

23

237

0.533

0.1555-1.826

 

0.4398

Musculoskeletal Sympt.

No Symptoms

31

42

52

208

3.648

2.101-6.333

 

< 0.0001**

Renal/Hepatobilary sympt.

No Symptoms

1

72

18

242

0.2245

0.02947-1.711

 

0.142

Pancreatitis Sympt.

No Symptoms

2

71

10

250

0.8423

0.1805-3.931

 

1.0000

Appendectomy

No Appendectomy

7

66

25

235

1.205

0.4997-2.905

 

0.6427

Growth Failure

No Growth Failure

2

71

10

250

0.8423

0.1805-3.931

 

1.0000

Abscess/Fistula

No Abscess/Fistula

19

54

33

227

2.943

1.559-5.556

 

0.0019**

Infection

No Infection

4

69

9

251

1.932

0.5781-6.460

 

0.2834

Diabetes

No Diabetes

1

72

4

256

1.059

0.1165-9.623

 

1.0000

Stricture/Bowel/Obstruction

No Stricture/Bowel/Obstruction

11

62

25

235

2.015

0.9419-4.313

 

0.0758

 

*Odds Ratio

**Confidence Interval