Table 3: Pharmacokinetics parameters obtained following oral administration of marketed capsules and the test to rabbits (mean ± SD, n = 3).

Parameters Marketed tablets Test
Tmax (min) 30 23.33 ± 5.77
Cmax (ng/mL) 476.13 ± 44.84 686.06 ± 69.94*
t1/2 (min) 44.11 ± 1.79 52.41 ± 8.45
AUC0-τ (min•ng/mL) 39011.55 ± 6637.08 54180.11 ± 6483.16*
MRT0-τ (min) 78.48 ± 3.88 75.51 ± 1.16
Relative bioavailability (%) 100 138.88

*p < 0.05 vs. marketed capsules.