Table 2: Univariate regression analysis of risk factor for gastric GIST ulceration.
|
Variable |
Valid data |
Total |
With ulceration (n = 40) |
Without ulceration (n = 90) |
P value (95%) |
|
Age (years) |
130 |
69 (59-76) |
71 |
68 |
0.49 |
|
Gender Males |
130 |
66 (50.8%) 64 (49.2%) |
23 (57.5%) 17 (42.5%) |
43 (47.8%) 47 (52.2%) |
0.306 |
|
H. pylori infection Positive |
109 |
23 (21.1%) |
10 (27.8%) |
13 (17.8%) |
0.230 |
|
Antiplatelets drugs |
130 |
39 (30%) |
13 (32.5%) |
26 (28.9%) |
0.678 |
|
PPI |
129 |
35 (27.1%) |
12 (30%) |
23 (25.8%) |
0.623 |
|
Metastasis |
128 |
10 (7.8%) |
4 (10.5%) |
6 (6.7%) |
0.482 |
|
Size (cm) |
129 |
4.5 (3-7) |
5 (3.2-7) |
4.25 (2.87-7) |
0.217 |
|
Ki-67 (%) |
107 |
3.4% (1-7%) |
5% (2.7-10%) |
3% (1-5.5%) |
0.016 |
|
Mitotic count (#/50 HPF) |
114 |
2.75 (1-5) |
3 (2-6.5) |
2 (1-4.5) |
0.015 |
|
INR |
120 |
1.01 (0.98-1.12) |
1.07 (0.99-1.18) |
1.01 (0.97-1.09) |
0.021 |
|
Lesion Location |
130 |
Upper stomach (cardiafundus) |
0.006 |
||
|
40 (30.8%) |
19 (47.5%) |
21 (23.3%) |
|||
|
Lower stomach (bodyantrum) |
|||||
|
90 (69.2%) |
21 (52.5%) |
69 (76.7%) |
|||
GIST: gastrointestinal stromal tumor; PPI: proton pump inhibitors; HPF: high power field; INR: international normalized ratio.