Table 3: Definitions and criteria

A. Acute Kidney Injury Definitions [17,19]:

RIFLE (Risk/Injury/Failure/Loss/End stage)	AKIN (Acute Kidney Injury Network)
An increase in serum creatinine of ≥ 50% developing over < 7 days OR A urine output of < 0.5ml/kg/hr for >6 hours	An increase in serum creatinine of ≥ 0.3mg/dL or ≥ 50% developing over < 48 hours OR A urine outpuat of < 0.5ml/kg/hr for >6 hours

B. RIFLE and AKIN staging Definitions [17,19]:

Staging	Increase in serum creatinine
RIFLE	Risk: >1.5-fold from baseline or GFR decrease >25%	Injury: > 2-fold increase or GFR decrease >50%	Failure: >3-fold increase or GFR decrease 75% or creatinine ≥ 4.0mg/dL
AKIN	Stage 1: ≥ 0.3mg/dL or ≥ 1.5-2-fold from baseline	Stage 2: >2 to 3-fold	Stage 3: > 3-fold OR creatinine ≥ 4.0mg/dL or on renal replacement therapy

C. APACHE II Scoring System criteria [37]:

Rectal temperature	Creatinine
Mean arterial pressure	Hematocrit
Heart rate	White blood cell count
Respiratory rate	Glasgow coma score
A-a gradient	Age
pH or bicarbonate level	Chronic disease
Sodium	Potassium

D. SOFA Scoring criteria [38]:

Ratio of arterial oxygen tension to fraction of inspired oxygen

Amount of vasopressor support

Bilirubin level

Platelet level

Glasgow coma score

Serum creatinine or urine output