Table 1: Comparison of patient characteristics according to the era of diagnosis.
| Variable | Era 1974-1994 | Era 1995-2014 | P value |
| (N = 45) | (N = 62) | ||
| Mean Age at diagnosis (SD) | 24.3 (15.3) | 29.8 (16.6) | 0.124 |
| % Male/female | 51/49 | 60/40 | 0.378 |
| % with Interstitial Fibrosis | 0 | 31 | < 0.001 |
| % with proliferative disease | 31 | 6 | 0.001 |
| % with family history | 80 | 75 | 0.741 |
| % with hearing defect | 24 | 38 | 0.349 |
| % with lens defect | 0 | 6 | 0.447 |
| Median creatinine at diagnosis (IQR) | 80 (60-88) | 95 (67-219) | 0.182 |
| Mean age at ESKD (SD) | 28 (9.8) | 33 (13.1) | 0.21 |