Table 2: Comparison of some variables according to on-treatment renal dysfunction.
Variable |
Renal Dysfunction (%) n = 12 |
Absence of Renal Dysfunction (%) n = 15 |
p-Value |
Sex (female) |
8 (67) |
7 (47) |
0.26 |
Age (≥ 65 years) |
4 (33.3) |
2 (13.3) |
0.22 |
Comorbidities |
|
|
|
Hypertension |
4 (33.3) |
4 (26.7) |
0.51 |
Diabetes |
4 (33.3) |
3 (20) |
0.36 |
Gout |
2 |
0 |
0.18 |
Chronic kidney disease |
1 |
0 |
0.44 |
Medication |
|
|
|
Angiotensin blocker |
4 (33.3) |
4 (26.7) |
0.51 |
Metformin |
3 (25) |
2 (13.3) |
0.4 |
Diuretic |
2 (16.7) |
1 (6.7) |
0.4 |
Biological data (baseline) |
|
|
|
Hemoglobin (g/dl) |
12.8 ± 1.3 |
12.9 ± 1.3 |
0.67 |
Alanine amino-transferase (UI/l) |
60.5 (27.5-77.0) |
67.8 (51.8-79.2) |
0.35 |
Aspartate amino-transferase (UI/l) |
68.5 (29.0-92.0) |
51.0 (47.1-66.5) |
0.8 |
Genotype 1 |
2 (66.7) |
5 (55.6) |
0.6 |
Treatment regimen |
|
|
|
Sofosbuvir + Velpatasvir |
10 (83.3) |
12 (80) |
0.99 |
Sofosbuvir + Daclatasvir |
2 (16.7) |
3 (20) |