Table 2: Comparison of some variables according to on-treatment renal dysfunction.

Variable

Renal Dysfunction (%) n = 12

Absence of Renal Dysfunction (%) n = 15

p-Value

Sex (female)

8 (67)

7 (47)

0.26

Age (≥ 65 years)

4 (33.3)

2 (13.3)

0.22

Comorbidities

 

 

 

Hypertension

4 (33.3)

4 (26.7)

0.51

Diabetes

4 (33.3)

3 (20)

0.36

Gout

2

0

0.18

Chronic kidney disease

1

0

0.44

Medication

 

 

 

Angiotensin blocker

4 (33.3)

4 (26.7)

0.51

Metformin

3 (25)

2 (13.3)

0.4

Diuretic

2 (16.7)

1 (6.7)

0.4

Biological data (baseline)

 

 

 

Hemoglobin (g/dl)

12.8 ± 1.3

12.9 ± 1.3

0.67

Alanine amino-transferase (UI/l)

60.5 (27.5-77.0)

67.8 (51.8-79.2)

0.35

Aspartate amino-transferase (UI/l)

68.5 (29.0-92.0)

51.0 (47.1-66.5)

0.8

Genotype 1

2 (66.7)

5 (55.6)

0.6

Treatment regimen

 

 

 

Sofosbuvir + Velpatasvir

10 (83.3)

12 (80)

0.99

Sofosbuvir + Daclatasvir

2 (16.7)

3 (20)