Mean Serum Urea Level (mmol/l)

Women

Reference Values (2.5-7)

Men

Reference Values (3.0-7.5)

Before

After

Significant

p-value

(< 0.05)

Before

After

Significant

p-value

(< 0.05)

AZT + 3TC + NVP

4.25 ± 1.25

5.23 ± 2.16

4.39 ± 1.28

5.29 ± 2.61

AZT + TNF + NVP

4.76 ± 0.36

4.52 ± 2.0

4.49 ± 1.64

6.24 ± 2.94

3TC + TNF + EMB

4.06 ± 1.59

4.95 ± 2.0

3.82 ± 1.64

3.91 ± 3.17

D4T30 + 3TC + EFV

3.62 ± 1.60

4.59 ± 2.31

5.41 ± 0.58

3.99 ± 2.35

D4T40 + 3TC + NVP

3.70 ± 2.15

6.43 ± 1.27

Yes

5.43 ± 0.41

2.77 ± 0.69

Yes

ABC + 3TC + EFV

4.32 ± 0.23

4.07 ± 0.58

3.99 ± 0.0

4.82 ± 0.0

NA

TNF + 3TC + EFV

3.94 ± 0.82

3.23 ± 0.66

3.99 ± 0.47

3.33 ± 0.47

TNF + 3TC + EFV + CTM

4.60 ± 0.41

4.71 ± 0.91

3.99 ± 0.69

5.2 ± 0.45

Yes

TNF + 3TC + EFV + INH

3.08 ± 0.58

5.07 ± 0.35

yes

NA

NA

NA

TNF + 3TC + EFV + CTM + INH

4.16 ± 0.60

4.16 ± 0.33

4.93 ± 0.25

5.10 ± 0.53

TNF + 3TC

0.95 ± 1.12

1.54 ± 1.79

NA

NA

NA

Mean Serum Creatinine Level (µmol/l)

Women

Reference Values (53-115)

Men

Reference Values (88-150)

Before

After

Significant

p-value

(< 0.05)

Before

After

Significant

p-value

(< 0.05)

AZT + 3TC + NVP

85.1 ± 18.3

64.2 ± 11.3

Yes

91.9 ± 30.3

61.8 ± 18.7

AZT + TNF + NVP

56.2 ± 30.8

81.3 ± 14.5

Yes

44.2 ± 25.0

83.9 ± 18.7

Yes

3TC + TNF + EMB

70.2 ± 15.9

58.7 ± 15.7

79.5 ± 25.0

66.3 ± 31.2

D4T30 + 3TC + EFV

81.9 ± 25.8

32.0 ± 36.4

110.5 ± 18.7

75.1 ± 6.2

D4T40 + 3TC + NVP

72.3 ± 46.6

109.0 ± 70

Yes

79.5 ± 17.6

97.2 ± 15.3

ABC + 3TC + EFV

75.5 ± 33.09

72.8 ± 11.8

174.8 ± 0.0

96.2 ± 0.0

NA

TNF + 3TC + EFV

78.9 ± 17.6

84.9 ± 21.5

93.0 ± 15.8

94.1 ± 17.9

TNF + 3TC + EFV + CTM

80.4 ± 15.1

81.5 ± 15.3

82.2 ± 18.5

87.3 ± 17.3

TNF + 3TC + EFV + INH

70.8 ± 18.0

91.4 ± 8.95

NA

NA

NA

TNF + 3TC + EFV + CTM + INH

85.6 ± 12.7

82.7 ± 20.2

89.5 ± 31.3

74.4 ± 27.2

TNF + 3TC

77.9 ± 26.4

78.8 ± 24.7

NA

NA

NA