Table 4: Performance of the incorporation of the RAI and the NLR in subgroup analysis.

 

Total (n = 173)

Non-surgical patient (n = 103)

Subsequent AKI

Mortality

AKI-requiring RRT

  Subsequent AKI

Mortality

AKI-requiring RRT

RAI ≥ 8 & NLR ≥ 5.5

% (95% CI)

RAI ≥ 8 & NLR ≥ 5.5

% (95% CI)

RAI ≥ 8 & NLR ≥ 5.5

% (95% CI)

RAI ≥ 8 & NLR ≥ 5.5

% (95% CI)

RAI ≥ 8 & NLR ≥ 5.5

% (95% CI)

RAI ≥ 8 & NLR ≥ 5.5

% (95% CI)

AUC

0.6 (0.49-0.71)

0.62 (0.47-0.77)

0.54 (0.45-0.63)

0.57 (0.45-0.7)

0.58 (0.43-0.73)

0.88 (0.84-0.92)

Sensitivity

36.4 (17.2-59.3)

41.7 (15.2-72.3)

25.9 (11.1-46.3)

38.9 (17.3-64.3)

41.7 (15.2-72.3)

100 (29.2-100)

Specificity

83.4 (76.5-89)

82.6 (75.9-88.1)

82.2 (75-88)

75.3 (64.7-84)

74.7 (64.5-83.3)

75.8 (66.1-83.8)

PPV

24.2 (11.1-42.3)

15.2 (5.1-31.9)

21.2 (9-38.9)

25 (10.7-44.9)

17.9 (6.1-36.9)

11.1 (2.4-29.2)

NPV

90 (83.8-94.4)

95 (90-98)

85.7 (78.8-91.1)

85.3 (75.3-92.4)

90.7 (81.7-96.2)

100 (95.2-100)

RAI: Renal Angina Index; NLR: Neutrophil-to-Lymphocyte Ratio; AKI: Acute Kidney Injury; RRT: Renal Replacement Therapy; CI: Confidence Interval; AUC: Area under the Curve; PPV: Positive Predictive Value; NPV: Negative Predictive Value