Table 1: Association between improvement of disease after HU treatment and the presence of the polymorphic site (C>T) at position -158 Xmn I at the G-? promoter region in the S/S (i) and S/ß (ii) cohorts
| S/S patients |
T/T (%) (n=11) |
T/C (%) (n=6) |
C/C (%) (n=23) |
| Good responders |
91% (n=10) |
83.3% (n=5) |
- |
| Partial responders |
9% (n=1) |
16.7% (n=1) |
82.6% (n=19) |
| Non responders |
- |
- |
17.4% (n=4) |
| S/ß patients |
T/C (%) (n=5) |
C/C (%) (n=7) |
| Good responders |
60% (n=3) |
14.3% (n=1) |
| Partial responders |
20% (n=1) |
71.4% (n=5) |
| Non responders |
20% (n=1) |
14.3% (n=1) |