Table 3: Summary of the HbS/S haplotypes in patients treated with HU
Haplotype |
XmnI genotype |
response to HU |
Asian/Asian (n=11) |
T/T |
Good (n=10) |
|
|
Partial (n=1) |
|
|
None (n=0) |
Asian/CAR (n=1) |
T/C |
Good (n=1) |
|
|
Partial (n=0) |
|
|
None (n=0) |
Asian/Oman (n=4) |
T/C |
Good (n=3) |
|
|
Partial (n=1) |
|
|
None (n=0) |
Senegal/Oman (n=1) |
T/C |
Good (n=1) |
|
|
Partial (n=0) |
|
|
None (n=0) |
Benin/Benin (n=9) |
C/C |
Good (n=0) |
|
|
Partial (n=9) |
|
|
None (n=0) |
CAR/CAR (n=3) |
C/C |
Good (n=0) |
|
|
Partial (n=3) |
|
|
None (n=0) |
CAR/Oman (n=11) |
C/C |
Good (n=0) |
|
|
Partial (n=7) |
|
|
None (n=4) |