Table 3: KIR-HLA ligand matches/mismatches among CMV and non-CMV cases using binary logistic regression.

KIR-HLA ligand match-mismatch [CMV (n=27)] KIR-HLA ligand match-mismatch [Non-CMV (n=259) Mismatch Missing
KIR HLA Match Mismatch KIR/HLA± KIR HLA Match Mismatch KIR/HLA± p-value OR 95%CI p-value OR 95%CI
KIR2DL2 HLA-C1 7(28%) 9(38%) 11(40%) KIR2DL2 HLA-C1 88(32%) 100(36%) 90(32%) 0.131 0.21 0.14-1.20 0.031* 0.23 0.11-0.32
KIR2DL3 HLA-C1 11(42%) 5(19%) 11(40%) KIR2DL3 HLA-C1 119(43%) 61(22%) 97(35%) 0.231 0.64 0.44-1.15 0.081 0.63 0.41-1.42
KIR2DS2 HLA-C1 5(19%) 13(49%) 9(32%) KIR2DS2 HLA-C1 32(27%) 121(49%) 87(31%) 0.204 0.63 0.39-1.64 0.235 0.68 0.31-1.22
KIR2DS3 HLA-C1 5(18%) 14(52%) 8(30%) KIR2DS3 HLA-C1 72(26%) 164(59%) 32(11%) 0.063 0.41 0.13-0.59 0.431 0.61 0.23-0.98
KIR2DL1 HLA-C2 23(96%) 3(3%) 1(1%) KIR2DL1 HLA-C2 83(41%) 62(30%) 57(28%) 0.130 0.55 0.26-1.18 0.067 0.50 0.24-1.05
KIR2DS1 HLA-C2 15(20%) 29(38%) 11(41%) KIR2DS1 HLA-C2 88(31%) 119(43%) 71(25%) 0.121 0.68 0.31-1.10 0.031*/td> 0.12 0.09-0.31
KIR3DL1 HLA-BW4 15(46%) 11(28%) 19(25%) KIR3DL1 HLA-BW4 107(53%) 33(16%) 62(30%) 0.608 1.20 0.58-2.49 0.166 0.63 0.32-1.21
KIR3DS1 HLA-Bw4 7(26%) 11(41%) 9(33%) KIR3DS1 HLA-Bw4 77(28%) 119(43%) 80(29%) 0.014* 0.95 0.43-1.13 0.002* 0.46 0.26-0.66


*= p< 0.05 & statistically significant. Match: KIR receptor is expressed by the recipient and the corresponding HLA ligand is displayed by the allograft. Mismatch:
recipient displays a certain KIR receptor but the donor graft does not have the corresponding HLA ligand. KIR/HLA ± (Missing): When the allograft has a certain HLA allele but the recipient is lacking the corresponding receptor, or when recipient and allograft both are lacking the receptor as well as the corresponding HLA ligand.